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BioSupplyNet gives you lab protocols; tools for data retrieval, analysis, and visualization; and information about finding kits and other laboratory supplies. Read on...


CSH Perspectives cover

Cold Spring Harbor Perspectives in Biology

Neuronal Signaling through Endocytosis.
Katharina E. Cosker and Rosalind A. Segal
Vol. 6 (2)

CSH Perspectives in Medicine cover

Cold Spring Harbor Perspectives in Medicine

Oncogenic Mechanisms in Burkitt Lymphoma.
Roland Schmitz, Michele Ceribelli, Stefania Pittaluga, George Wright, and Louis M. Staudt
Vol. 4 (2)

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Cold Spring Harbor Protocols

Genetic Labeling of Neurons in Mouse Brain.
Z. Josh Huang, Hiroki Taniguchi, Miao He, Sandra Kuhlman
doi: 10.1101/pdb.top080374

Tips on Hybridizing, Washing, and Scanning Affymetrix Microarrays.
Manuel Ares Jr.
doi: 10.1101/pdb.prot080150

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Genes & Development

Astrocytes engage unique molecular programs to engulf pruned neuronal debris from distinct subsets of neurons.
Ozge E. Tasdemir-Yilmaz and Marc R. Freeman
Vol. 28 (1) 20–33.

Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint.
Nitobe London and Sue Biggins
Vol. 28 (2) 140–152.

Genome Research cover

Genome Research

Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia.
Pedro G. Ferreira, Pedro Jares, Daniel Rico, Gonzalo Gómez-López, Alejandra Martínez-Trillos, Neus Villamor, Simone Ecker, Abel González-Pérez, David G. Knowles, Jean Monlong, Rory Johnson, Victor Quesada, Sarah Djebali, Panagiotis Papasaikas, Mónica López-Guerra, Dolors Colomer, Cristina Royo, Maite Cazorla, Magda Pinyol, Guillem Clot, Marta Aymerich, Maria Rozman, Marta Kulis, David Tamborero, Anaïs Gouin, Julie Blanc, Marta Gut, Ivo Gut, Xose S. Puente, David G. Pisano, José Ignacio Martin-Subero, Nuria López-Bigas, Armando López-Guillermo, Alfonso Valencia, Carlos López-Otín, Elías Campo, and Roderic Guigó
Vol. 24 (2) 212–226.

This month Genome Research highlights cutting edge research in cancer genomics. In one study, featured on ScienceDaily and GenomeWeb, integration of human papilloma virus (HPV) increased genomic instability of the host genome in cervical, head and neck cancers. A molecular and clinical subdivision in chronic lymphocytic leukemia (CLL), which may aid in predicting time to treatment, is reported in another study. Also in this issue, extensive intra-tumor heterogeneity in ovarian cancer genomes is identified and may contribute to high rates of cancer recurrence. These studies were profiled on GenomeWeb’s The Daily Scan, and can be found, along with the other cancer genomics studies from this issue, here.

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Learning & Memory

A novel role for the rat retrosplenial cortex in cognitive control.
Andrew J.D. Nelson, Emma L. Hindley, Josephine E. Haddon, Seralynne D. Vann, and John P. Aggleton
Vol. 21 (2) 90–97.

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RNA

Identification of expressed and conserved human noncoding RNAs.
Morten Muhlig Nielsen, Disa Tehler, Søren Vang, Frantisek Sudzina, Jakob Hedegaard, Iver Nordentoft, Torben Falck Ørntoft, Anders H. Lund, and Jakob Skou Pedersen
Vol. 20 (2) 236–251.