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Cold Spring Harbor Perspectives in Biology

The EGFR Family: Not So Prototypical Receptor Tyrosine Kinases.
Mark A. Lemmon, Joseph Schlessinger, and Kathryn M. Ferguson
Vol. 6 (4)

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Cold Spring Harbor Perspectives in Medicine

Heart Transplantation: Challenges Facing the Field.
Makoto Tonsho, Sebastian Michel, Zain Ahmed, Alessandro Alessandrini, and Joren C. Madsen
Vol. 4 (5)

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Cold Spring Harbor Protocols

Measuring the Ca2+-Binding Kinetics of Proteins.
Guido C Faas and Istvan Mody
doi: 10.1101/pdb.top066258

Subcapsular Transplantation of Tissue in the Kidney.
Leonard D. Shultz, Neal Goodwin, Fumihiko Ishikawa, Vishnu Hosur, Bonnie L. Lyons, and Dale L. Greiner
doi: 10.1101/pdb.prot078089

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Genes & Development

Evolutionally dynamic L1 regulation in embryonic stem cells.
Nathaly Castro-Diaz, Gabriela Ecco, Andrea Coluccio, Adamandia Kapopoulou, Benyamin Yazdanpanah, Marc Friedli, Julien Duc, Suk Min Jang, Priscilla Turelli, and Didier Trono
Vol. 28 (13) 1397–1409.

piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells.
Dubravka Pezic, Sergei A. Manakov, Ravi Sachidanandam, and Alexei A. Aravin
Vol. 28 (13) 1410–1428.

Lineage of origin in rhabdomyosarcoma informs pharmacological response.
Jinu Abraham, Yaiza Nuñez-Álvarez, Simone Hettmer, Elvira Carrió, Hung-I Harry Chen, Koichi Nishijo, Elaine T. Huang, Suresh I. Prajapati, Robert L. Walker, Sean Davis, Jennifer Rebeles, Hunter Wiebush, Amanda T. McCleish, Sheila T. Hampton, Christopher R.R. Bjornson, Andrew S. Brack, Amy J. Wagers, Thomas A. Rando, Mario R. Capecchi, Frank C. Marini, Benjamin R. Ehler, Lee Ann Zarzabal, Martin W. Goros, Joel E. Michalek, Paul S. Meltzer, David M. Langenau, Robin D. LeGallo, Atiya Mansoor, Yidong Chen, Mònica Suelves, Brian P. Rubin, and Charles Keller
Vol. 28 (14) 1578–1591.

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Genome Research

Analysis of 41 plant genomes supports a wave of successful genome duplications in association with the Cretaceous-Paleogene boundary.
Kevin Vanneste, Guy Baele, Steven Maere, and Yves Van de Peer
Vol. 24 (8) 1334–1347.

This month Genome Research published a study examining ancient whole genome duplication events in 41 different plant species. Using whole genome and transcriptome sequencing, the authors were able to determine that the plants had duplication events clustering with the Cretaceous-Paleogene mass extinction. This event, occurring roughly 66 million years ago, is associated with the loss of about 75% of the species on Earth, including dinosaurs. The authors propose that stress and extinction may have promoted the establishment of polyploid species, which contain more than two sets of chromosomes. The study is profiled on GenomeWeb’s The Daily Scan.

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Learning & Memory

A novel role for the rat retrosplenial cortex in cognitive control.
Andrew J.D. Nelson, Emma L. Hindley, Josephine E. Haddon, Seralynne D. Vann, and John P. Aggleton
Vol. 21 (2) 90–97.

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RNA

Small RNA profiling and characterization of piRNA clusters in the adult testes of the common marmoset, a model primate.
Takamasa Hirano, Yuka W. Iwasaki, Zachary Yu-Ching Lin, Masanori Imamura, Naomi M. Seki, Erika Sasaki, Kuniaki Saito, Hideyuki Okano, Mikiko C. Siomi, and Haruhiko Siomi
Vol. 20 (8) 1223–1237.