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BioSupplyNet gives you lab protocols; tools for data retrieval, analysis, and visualization; and information about finding kits and other laboratory supplies. Read on...

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We are offering special pre-publication pricing on three upcoming titles: receive 25% off when you place your order directly with us! Discounts apply to direct purchases by individual customers only.

(Note: You do not need to be a member of our Discount Program to receive this discount; however, if you are a member or if you register on our site to become a member of our Discount Program, you will receive an additional 10% discount.)

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List price: $135
Sale price: $101.25
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List price: $135
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List price: $135
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Imaging: A Laboratory Manual cover image

Imaging: A Laboratory Manual Kindle Edition

FREE SAMPLE!

The Kindle version of this must-have resource for molecular biologists is now available in electronic format (via Kindle app) for your iPad, iPhone, Android, Windows PC, Mac, Windows Phone 7, Blackberry, or Kindle device! Imaging: A Laboratory Manual is the cornerstone of our new laboratory manual series on imaging techniques, which have become tremendously valuable in nearly every field of biological research. This volume is designed as a general reference and describes the theory and practice of a wide array of imaging methods, but becomes an even more effective research tool in an electronic format. Visit the Kindle Store and download the free sample material to see for yourself how this manual comes to life with live links and beautiful full-color illustrations.

The Nucleus cover image

The Nucleus

“...Misteli is one of the most creative and productive recent arrivals in the nucleus field, as is his former postdoc mentor, David Spector....every chapter in the book was written by undeniable world leaders....The coverage is complete in that there is no structure or function of the nucleus that does not have a chapter....the book has all of the hallmarks of the fine publishing house that is Cold Spring Harbor Laboratory Press....The result is a book about the nucleus that will not be surpassed anytime soon.”

—The FASEB Journal

 

“The 28 chapters are organized to provide a comprehensive overview of nuclear compartments and their components (e.g. nuclear membrane, nuclear pore complex, chromosome territories, Cajal body, nucleolus), to discuss how this organization relates to function (transcription, DNA replication and repair, RNA processing) and to describe the defects in nuclear organization in human disease. The focus is primarily on the nucleus in mammalian cells, but there are also discussions on other simpler model organisms — budding yeast, Caenorhabditis elegans and Drosophila. Each chapter is relatively short and accessible, making this a great resource to dip into. Illustrations are used sparingly but are well chosen....if your interest in the nucleus is piqued, then this book is a good place to start.”

—Development
Imaging in Developmental Biology cover image

Imaging in Developmental Biology

“Imaging in Developmental Biology is an excellent resource from which both novices and experienced researchers can obtain current state-of-the-art embryo-imaging protocols for studying key developmental events, such as cell-fate determination, morphogen gradient formation, cell-cell interactions, cell migration and morphogenesis....comment often expressed was: “I did not know that we could do so much!” Upon first perusal, this comprehensive book seems almost overwhelming with an impressive 57 chapters and seven appendices. But it does contain just about everything known about imaging embryos. This is not surprising as the volume is based, in part, on the popular and excellent Cold Spring Harbor imaging course....The book is pleasant to read, with its clever use of illustrations, photos and online protocol videos....we highly recommend this book and hope that multidisciplinary collaborative expertise in biology, imaging, image analysis, computer science, visualization and database construction will continue to fast-forward 4D imaging techniques and, consequently, our knowledge of development.”

—Development
RNA: Life’s Indispensable Molecule cover image

RNA: Life’s Indispensable Molecule

“Darnell’s book is not only a bible but a lexicon. Every key experiment from the past seven decades that shaped current appreciation of the multiple roles of cellular RNA molecules is described with clarity in several succinct sentences.... RNA: Life’s Indispensable Molecule, should be required reading, as well as a handy desktop reference, for everyone charged with teaching gene expression on any level. It really does say it all.”

—Joan A. Steitz in Science

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The Complete, Renowned Book Series Now Online!

From the Preface of Nucleases: In August 1981, at the suggestion of Jim Watson, a meeting was held at Cold Spring Harbor on the topic of nucleases. The idea was to bring together people who study these enzymes, but who do not usually meet as a group because their individual interests in nucleases are primarily in the context of some other field. Historically, nucleases have not usually been considered a field in their own right, rather they have been studied because of their role in some particular biological phenomena such as the four R’s — Replication, Recombination, Repair, and Restriction.

The CSH Monograph Archive offers the complete collection of scholarly monographs published by Cold Spring Harbor Laboratory Press from 1970 to 2009. The archive’s 59 full-text volumes provide the life science community with definitive reviews of progress in areas of molecular, cell, and developmental biology, genetics, evolutionary biology, neuroscience, cancer biology, and molecular pathology. Each text is written and commissioned by foremost researchers in their particular discipline.

It is available online as a complete collection for one-time purchase (with perpetual access) or on pay-per-view basis by book chapter.

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At the Helm cover image   At the Bench cover image   The Eighth Day of Creation cover image   Max Perutz and the Secret of Life cover image
Sydney Brenner: A Biography cover image   Francis Crick: Hunter of Life's Secrets cover image   Abraham Lincoln's DNA cover image   What a Time I Am Having cover image

Offer valid through 2/29/2012 on direct purchases by individual customers only.


Cold Spring Harbor Symposia 70 Year Online Archive graphic

Hundreds of important advances in biology were announced, debated, and distilled at the Cold Spring Harbor Symposia. These meetings, held each year on the tranquil grounds of one of the world’s leading research institutes, have been notable events in biomedical research since 1933. Now this essential archive, dating from 1933 to 2003, is available online for a one-time fee.


Top Sellers This Month
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RNA: Life's Indispensable Molecule
An Introduction to Nervous Systems
The Origins of Life
Essentials of Glycobiology, Second Edition
Cell-Cell Junctions
Generation and Interpretation of Morphogen Gradients
Visit our Sale Shelf for Special Discounts on Selected Items

Many new titles recently added!

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CSH Perspectives cover image

A new type of online review journal

• Spanning the complete spectrum of the molecular life sciences

• Article collections that build month by month

• Written and commissioned by experts in each field

Read these essential papers in this month’s issue:

The matrisome: Richard Hynes catalogs ECM constituents.
Completion of genome sequences for many organisms allows a reasonably complete definition of the complement of extracellular matrix (ECM) proteins. In mammals this “core matrisome” comprises ˜300 proteins. In addition there are large numbers of ECM-modifying enzymes, ECM-binding growth factors, and other ECM-associated proteins. Read the full text.

Steven Benner discusses strategies for studying RNA’s role in the origin of life.
No community-accepted scientific methods are available today to guide studies on what role RNA played in the origin and early evolution of life on Earth. Further, a definition-theory for life is needed to develop hypotheses relating to the “RNA First” model for the origin of life. Read the full text.

Synaptic vesicle exocytosis: Thomas Südhof reviews how neurotransmitters are released at the synaptic cleft.
Presynaptic nerve terminals release neurotransmitters by synaptic vesicle exocytosis. Membrane fusion mediating synaptic exocytosis and other intracellular membrane traffic is affected by a universal machinery that includes SNARE (for “soluble NSF-attachment protein receptor”) and SM (for “Sec1/Munc18-like”) proteins. Read the full text.

Visit here for this month’s complete table of contents and to learn more.

Cold Spring Harbor Perspectives in Biology

The Authoritative View

www.cshperspectives.org

Books available for the Kindle graphic

Imaging: A Laboratory Manual cover art   The Honest Look cover art   Sydney Brenner: A Biography cover art   Experimental Heart cover art   Genes and Signals cover art   A Genetic Switch cover art   Abraham Lincoln's DNA cover art   The Strongest Boy in the World, Updated Edition cover art