© 2003 • 352 pp., appendix
Paperback w/CD-ROM • ISBN  978-080534722-7

This book is co–published with Benjamin Cummings. Requests for textbook examination copies and orders for course adoptions should be sent to:
Benjamin Cummings Pearson Education
1301 Sansome Street
San Francisco, CA 94111-9328 www.aw.com/bc

Discovering Genomics, Proteomics, and Bioinformatics is the first textbook which combines integrated web exercises with a problem–solving approach to train students in basic hands–on genomic analysis. The authors present global problems, then provide the tools of genomic analysis to help students dissect the answer, thus encouraging critical–thinking skills. Microarray images and all art and figures from the text are available on the free art CD–ROM. The Discovering Genomics, Proteomics, and Bioinformatics Companion Website www.geneticsplace.com helps students learn about cutting–edge research and visualize complex processes. This integrated learning package sets the standard for material in the exciting new field of genomics.

FEATURES:
First genomics textbook written for students that focuses on the process of doing genomic analysis and thinking from a genomics perspective.
Inquiry approach gives students hands–on practice and builds problem solving skills. Students learn to use databases and how to extract pertinent information.
Math Minutes supply brief tutorials that reveal the math behind the biology and illustrate how investigators apply math in solving specific biology problems.
Discovery Questions appear throughout each chapter and ask students to consider what is happening in a particular example or case study, thus engaging students in taking a genomic approach to real–world problems.
Case studies and real–world examples provide a context for understanding the experiments and results.
Integrated multimedia and web resources direct students to a full methods index, relevant web links, and animations that allow them to research and analyze real genomics data as they work their way through each chapter. Icons in the text alert students to these media tools.

  “Discovering Genomics, Proteomics, and Bioinformatics does two very important things: It illustrates how to traverse the bridge between traditional single molecule studies and novel genomics/protoemics studies using bioinformatics as a tool. Further, it does so in a manner that a student who is new to either (or both) of these fields can clearly grasp the underlying biological and informatics concepts.”
      —Cell Biology Education

  “The authors have produced an outstanding volume for anyone requiring an introduction to the emerging fields of genomics and proteomics. The text is organized into four units, each three chapters in length, that focus on Genome Sequences, Genome Expression, Whole Genome Perspective and, finally, Transition from Genetics to Genomics: Medical Case Studies.  The authors use a straightforward writing style to lead readers through the material covered by raising a series of questions and using them as section headings....This volume is well–referenced and illustrated.  It comes with a CD–ROM that includes all of the figures in the text and several additional illustrations that are referred to but not included in the printed material. I would highly recommend Discovering Genomics, Proteomics, and Bioinformatics to both students and teachers. This book is destined to become another classic from Cold Spring Harbor Laboratory Press.”
      —The Quarterly Review of Biology

GENOMIC SEQUENCES

Genome Sequence Acquisition and Analysis
Genome Sequences to Answer Interesting Questions
Genomic Variations

GENOMIC EXPRESSION

Basic Research with DNA Microarrays
Applied Research with Microarrays
Proteomics

WHOLE GENOME PERSPECTIVE

Genomic Circuitry in Single Genes
Integrated Genomic Circuits
Modeling Whole-Genome Circuits

TRANSITION FROM GENETICS TO GENOMICS: MEDICAL CASE STUDIES

Whats Wrong with My Child?
Why Can't I Just Take a Pill to Lose Weight?
Why Can't We Cure More Diseases?
Appendix A: Introduction to Genomics on the Web

SUPPLEMENTS:

General Supplements
Discovering Genomics, Proteomics, and Bioinformatics Companion Website www.geneticsplace.com Fully integrated with the text, this site provides a methods index, live links to all websites and databases referenced in the text, additional resources, math tutorials, and 3–D animations of processes students have difficulty visualizing. In addition, all the art and the figures from the text are available for downloading.

Instructor Supplement
Printed Instructors Manual
ISBN 0–8053–4726–7
Includes sample syllabi, answers to all the Discovery Questions found in the text, as well as additional questions for review.

Student Supplements
Discovering Genomics, Proteomics, and Bioinformatics Art CD–ROM
ISBN 0–8053–4734–8
This CD–ROM includes approximately 50 microarray images discussed in the book, and all art and figures from the text. Included FREE with every new copy of the text.