© 2010 • 308 pp., illus., index
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Signaling by diffusible morphogens, such as Hedgehog, Wingless, TGF-

Preface

Morphogen Gradient Formation

Ortrud Wartlick, Anna Kicheva, and Marcos González-Gaitán

Models for the Generation and Interpretation of Gradients

Hans Meinhardt

Robust Generation and Decoding of Morphogen Gradients

Naama Barkai and Ben-Zion Shilo

The Measure of Success: Constraints, Objectives, and Tradeoffs in Morphogen-mediated Patterning

Arthur D. Lander, Wing-Cheong Lo, Qing Nie, and Frederic Y.M. Wan

Shaping Morphogen Gradients by Proteoglycans

Dong Yan and Xinhua Lin

Forming and Interpreting Gradients in the Early Xenopus Embryo

James C. Smith

Systems Biology of the Self-regulating Morphogenetic Gradient of the Xenopus Gastrula

Jean-Louis Plouhinec and E.M. De Robertis

Nodal Morphogens

Alexander F. Schier

Gradients in Planarian Regeneration and Homeostasis

Teresa Adell, Francesc Cebriò, and Emili Saló

Axial Patterning in Hydra

Hans R. Bode

Regulation of Organ Growth by Morphogen Gradients

Gerald Schwank and Konrad Basler

Signaling Gradients during Paraxial Mesoderm Development

Alexander Aulehla and Olivier Pourquié

Vertebrate Limb Development: Moving from Classical Morphogen Gradients to an Integrated 4-Dimensional Patterning System

Jean-Denis Bénazet and Rolf Zeller

Establishing and Interpreting Graded Sonic Hedgehog Signaling during Vertebrate Neural Tube Patterning: The Role of Negative Feedback

Vanessa Ribes and James Briscoe

Gradients in the Brain: The Control of the Development of Form and Function in the Cerebral Cortex

Stephen N. Sansom and Frederick J. Livesey

Graded Dorsal and Differential Gene Regulation in the Drosophila Embryo

Gregory T. Reeves and Angelike Stathopoulos

Gradients and the Specification of Planar Polarity in the Insect Cuticle

David Strutt

Chemical Gradients and Chemotropism in Yeast

Robert A. Arkowitz

Forming Patterns in Development without Morphogen Gradients: Scattered Differentiation and Sorting Out

Robert R. Kay and Christopher R.L. Thompson

Index