The Biology of Lipids: Trafficking, Regulation, and Function, Second Edition

Click to Enlarge				The Biology of Lipids: Trafficking, Regulation, and Function, Second Edition Subject Area(s): Cell Biology; Biochemistry; Plant Biology Edited by Robert G. Parton, The University of Queensland; Kai Simons, Max-Planck-Institute of Molecular Cell Biology and Genetics and Lipotype GmbH

				Due April 2024 • 300 pages (approx.), illustrated, index Hardcover • ISBN 978-1-621824-74-9

Description Contents Description Lipids are the major component of cell and organelle membranes. They are essential for maintaining cell integrity and defining distinct subcellular compartments but also play important roles in a variety of other cellular processes. Membrane fission and fusion and movement of lipid-enveloped vesicles underlie the majority of protein trafficking in cells and are critical for the function of synapses in the nervous system. In addition, lipids participate in numerous signaling pathways that connect cell-surface receptors with intracellular effectors. Written and edited by experts in the field, this new edition of the highly successful Cold Spring Harbor volume on lipids provides a comprehensive update on lipid cell biology. The contributors discuss the organization of lipids in cellular membranes, membrane biophysics, and the phase transitions lipids undergo. They examine tools for analysis of lipids and lipid modifications. They also review our understanding of lipid sorting and its role in maintenance of organelle identity. The volume covers the functions of lipids in various signal transduction pathways, as well as the roles of cholesterol, extracellular vesicles, and the importance of lipids in the unfolded protein response. Including discussion of the importance of lipids for synaptic activity and memory, it is an indispensable reference not only for cell biologists and biochemists but neurobiologists and any other researchers interested in the importance of lipids in cell physiology. Contents Seeing the Membrane from Both Sides Now: Lipid Asymmetry and Its Strange Consequences Milka Doktorova, Ilya Levental, and Frederick A. Heberle A Survey of Models of Cell Membranes: Towards a New Understanding of Membrane Organization Satyajit Mayor, Abrar Bhat, and Akihiro Kusumi The Membrane Phase Transition Gives Rise to Responsive Plasma Membrane Structure and Function Sarah A. Shelby and Sarah L. Veatch Lipid Sorting and Organelle Identity Yeongho Kim and Christopher G. Burd Endocytic Roles of Glycans on Proteins and Lipids Ludger Johannes, Massiullah Shafaq-Zadah, Estelle Dransart, Christian Wunder, and Hakon Leffler ER Membrane Homeostasis and the Unfolded Protein Response Robert Ernst, Mike F. Renne, Aamna Jain, and Alexander von der Malsburg Intracellular Cholesterol Trafficking Elina Ikonen and Vesa M. Olkkonen Phospholipase Modulation of Synaptic Membrane Landscape: Driving Force Behind Memory Formation? Tristan P. Wallis and Frédéric A. Meunier Phosphoinositides in New Spaces Elizabeth Michele Davies, Christina Anne Mitchell, and Harald Alfred Stenmark Chemical Approaches for Measuring and Manipulating Lipids at the Organelle Level Masaaki Uematsu and Jeremy M. Baskin Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function Takeshi Harayama and Bruno Antonny The Role of Membrane Lipids in the Formation and Function of Caveolae Anne K. Kenworthy, Bing Han, Nicholas Ariotti, and Robert G. Parton RAS GTPases and Interleaflet Coupling in the Plasma Membrane Junchen Liu, Neha Arora, and Yong Zhou Lipids in Extracellular Vesicles: What Can Be Learnt About Membrane Structure and Function? Tore Skotland, Alicia Llorente, and Kirsten Sandvig Membrane Epilipidome – Lipid Modifications, Their Dynamics and Functional Significance Sider Penkov and Maria Fedorova Cholesterol, Eukaryotic Lipid Domains, and an Evolutionary Perspective of Transmembrane Signaling Yan Shi, Hefei Ruan, Yanni Xu, and Chunlin Zo How Neuromembrane Lipids Modulate Membrane Proteins: Insights from G Protein-Coupled Receptors (GPCRs) and Receptor Tyrosine Kinases (RTKs) Mykhailo Girych, Waldemar Kulig, Giray Enkavi, and Ilpo Vattulainen Index

The Biology of Lipids: Trafficking, Regulation, and Function, Second Edition

Description

Contents