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Imaging in Developmental Biology: A Laboratory Manual

Edited By James Sharpe, EMBL-CRG Systems Biology Unit, Barcelona, Spain; Rachel Wong, University of Washington; Series Editor, Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 883 pp., illus., index
Paperback • $169.00 $118.30 • ISBN 978-0-879699-40-6

New imaging technologies have revolutionized the study of developmental biology. Where researchers once struggled to connect events at static timepoints, imaging tools now offer the ability to visualize the dynamic form and function of molecules, cells, tissues, and whole embryos throughout the entire developmental process. Imaging in Developmental Biology: A Laboratory Manual, a new volume in Cold Spring Harbor Laboratory Press’ Imaging series, presents a comprehensive set of essential visualization methods. The manual features primers on live imaging of a variety of standard model organisms including C. elegans, Drosophila, zebrafish, Xenopus, avian species, and mouse. Further techniques are organized by the level of visualization they provide, from cells to tissues and organs to whole embryos. Methods range from the basics of labeling cells to cutting-edge protocols for high-speed imaging, optical projection tomography, and digital scanned laser light-sheet fluorescence. Imaging has become a required methodology for developmental biologists, and Imaging in Developmental Biology: A Laboratory Manual provides the detailed explanations and instructions for mastering these necessary techniques.

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Imaging in Developmental Biology: A Laboratory Manual

Edited By James Sharpe, EMBL-CRG Systems Biology Unit, Barcelona, Spain; Rachel Wong, University of Washington; Series Editor, Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 883 pp., illus., index
Hardcover • $246.00 $172.20 • ISBN 978-0-879699-39-0

New imaging technologies have revolutionized the study of developmental biology. Where researchers once struggled to connect events at static timepoints, imaging tools now offer the ability to visualize the dynamic form and function of molecules, cells, tissues, and whole embryos throughout the entire developmental process. Imaging in Developmental Biology: A Laboratory Manual, a new volume in Cold Spring Harbor Laboratory Press’ Imaging series, presents a comprehensive set of essential visualization methods. The manual features primers on live imaging of a variety of standard model organisms including C. elegans, Drosophila, zebrafish, Xenopus, avian species, and mouse. Further techniques are organized by the level of visualization they provide, from cells to tissues and organs to whole embryos. Methods range from the basics of labeling cells to cutting-edge protocols for high-speed imaging, optical projection tomography, and digital scanned laser light-sheet fluorescence. Imaging has become a required methodology for developmental biologists, and Imaging in Developmental Biology: A Laboratory Manual provides the detailed explanations and instructions for mastering these necessary techniques.

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Imaging in Neuroscience: A Laboratory Manual

Edited By Fritjof Helmchen, Brain Research Institute, University of Zurich, Switzerland; Arthur Konnerth, Institute for Neurosciences, Technical University Munich, Germany; Series Editor, Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 1084 pp., illus., index
Paperback • $200.00 $140.00 • ISBN 978-0-879699-38-3

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Imaging in Neuroscience: A Laboratory Manual

Edited By Fritjof Helmchen, Brain Research Institute, University of Zurich, Switzerland; Arthur Konnerth, Institute for Neurosciences, Technical University Munich, Germany; Series Editor, Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 1084 pp., illus., index
Hardcover • $287.00 $200.90 • ISBN 978-0-879699-37-6

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Imaging: A Laboratory Manual

Edited By Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 952 pp., illus. (182 color, 97 b/w), appendices, index
Trim size: 8-1/2” x 10-7/8”
Hardcover • $246.00 $172.20 • ISBN 978-0-879699-35-2

In recent years, imaging has rapidly become a tremendously valuable approach in nearly every field of biological research. Finding the right method and optimizing it for data collection can be a daunting process, even for an established imaging laboratory. Imaging: A Laboratory Manual is the cornerstone of a new laboratory manual series, designed as an essential guide for investigators who need these visualization techniques. This first volume is meant as a general reference for all fields, and describes the theory and practice of a wide array of imaging methods. From the basic chapters on optics, equipment and labeling to detailed explanations of advanced, cutting-edge methods like PALM, STORM, light sheet and high speed microscopy, Imaging: A Laboratory Manual is a vital resource for the modern biology laboratory.

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Imaging: A Laboratory Manual

Edited By Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 952 pp., illus. (182 color, 97 b/w), appendices, index
Trim size: 8-1/2” x 10-7/8”
Paperback • $169.00 $118.30 • ISBN 978-0-879699-36-9

In recent years, imaging has rapidly become a tremendously valuable approach in nearly every field of biological research. Finding the right method and optimizing it for data collection can be a daunting process, even for an established imaging laboratory. Imaging: A Laboratory Manual is the cornerstone of a new laboratory manual series, designed as an essential guide for investigators who need these visualization techniques. This first volume is meant as a general reference for all fields, and describes the theory and practice of a wide array of imaging methods. From the basic chapters on optics, equipment and labeling to detailed explanations of advanced, cutting-edge methods like PALM, STORM, light sheet and high speed microscopy, Imaging: A Laboratory Manual is a vital resource for the modern biology laboratory.

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Immune Tolerance

Edited By Diane J. Mathis, Harvard Medical School; Alexander Y. Rudensky, Howard Hughes Medical Institute and Memorial Sloan-Kettering Cancer Center

© 2013 • 168 pp., illus. (2 B&W, 20 4C), index
Hardcover • $135 • ISBN 978-0-879698-95-9

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Immunoreceptor Signaling

Edited By Lawrence E. Samelson, National Institutes of Health; Andrey Shaw, Washington University School of Medicine

© 2011 • 282 pp., illus. (49 color, 7 b/w), index
Trim size: 7” x 10”
Hardcover • $135 $33.75 • ISBN 978-0-879698-96-6

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Incurable: A Life after Diagnosis

By Charles Harris

© 2011 • 280 pp., illus.
Hardcover • $31.00 • ISBN 978-1-936113-10-1

In March 2009, during a routine medical exam, Charles Harris learned that he had incurable cancer. Although a private man, he began a blog to keep family and friends current on his progress, and found a wider audience. From the blog was born Incurable, an account of a man’s struggle to live vibrantly and with courage in the face of a fatal illness. An entrepreneur and investor by profession, Charles Harris writes about living and dying, friendship and fellowship, sports and wine, race horses and recessions. His style is optimistic, direct, humorous, and companionable. Readers will find his voice brave, inspirational, and an eloquent reminder that an understanding of cancer remains an urgent goal in biomedicine. Proceeds from this book will be used by the Harris family in support of cancer research.

Read more about the book here.

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The Inside Story: DNA to RNA to Protein

Edited By Jan Witkowski, Cold Spring Harbor Laboratory

© 2005 • 382 pp., illus., index
Paperback • $29 $14.50 • ISBN 978-087969750-1