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The Biology of Plants
(Cold Spring Harbor Symposia on Quantitative Biology LXXVII)

Edited By Terri Grodzicker, Cold Spring Harbor Laboratory; Robert Martienssen, Cold Spring Harbor Laboratory; David Stewart, Cold Spring Harbor Laboratory; Bruce Stillman, Cold Spring Harbor Laboratory

Due June 2013 • 440 pp. (approx.), illus., index
(Hardcover edition includes online access; call for information and registration)
Hardcover • $318 • ISBN 978-1-621820-25-3

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Cystic Fibrosis: A Trilogy of Biochemistry, Physiology, and Therapy

Edited By John R. Riordan, The University of North Carolina at Chapel Hill; Richard C. Boucher, The University of North Carolina at Chapel Hill; Paul M. Quinton, University of California, San Diego School of Medicine

Due July 2013 • 400 pp.(approx.), illus. (approx. 37 4C; 11 B&W), index
Hardcover • $135 $101.25 • ISBN 978-1-936113-34-7

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Cell Survival and Cell Death

Edited By Eric H. Baehrecke, University of Massachusetts; Douglas R. Green, St. Jude Children's Research Hospital; Sally Kornbluth, Duke University; Guy S. Salvesen, Sanford-Burnham Medical Research Institute

Due August 2013 • 300 pp. (approx.), illus. (29 4C, 51 B&W), index
Hardcover • $135 • ISBN 978-1-936113-31-6

Cell death plays a critical role in development, normal physiology, and many diseases, including cancer. This short book describes our detailed understanding of the mechanisms involved in cell death signaling, covering signal transducers, caspases, Bcl2-family proteins, mitochondrial molecules, and IAPs, as well as the survival mechanisms that antagonize them. Cell death mechanisms involved in tumor suppression and cancer are also covered.

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Mitochondria

Edited By Douglas C. Wallace, Children's Hospital of Philadelphia, University of Pennsylvania; Richard J. Youle, National Institute of Neurological Disorders and Strokes, Porter Neuroscience Research Center

Due September 2013 • 300 pp.(approx.), illus., index
Hardcover • $135 • ISBN 978-1-936113-35-4

Mitochondria are intracellular organelles that power the cell by metabolizing glucose and other energy sources to generate ATP. They are also critical in programmed cell death, and dysfunction of mitochondrial components is implicated in numerous muscle and neurodegenerative disorders, including Parkinson’s disease. This volume contains contributions examining the evolution and normal function of mitochondria in cells, as well as their roles in various pathologies.

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Lab Math: A Handbook of Measurements, Calculations, and Other Quantitative Skills for Use at the Bench, 2nd edition

By Dany Spencer Adams

Due September 2013 • 350pp. (approx.), illus., index
Concealed wire binding • $59 • ISBN 978-1-936113-71-2

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Mammalian Development: Networks, Switches, and Morphogenetic Processes

Edited By Patrick P.L. Tam, Children’s Medical Research Institute; W. James Nelson, Stanford University; Janet Rossant, The Hospital for Sick Children

© 2013 • 520 pp., illus. (120 4C, 21 B&W), index
Hardcover • $155 • ISBN 978-1-936113-24-8

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Immune Tolerance

Edited By Diane J. Mathis, Harvard Medical School; Alexander Y. Rudensky, Howard Hughes Medical Institute and Memorial Sloan-Kettering Cancer Center

© 2013 • 168 pp., illus. (2 B&W, 20 4C), index
Hardcover • $135 • ISBN 978-0-879698-95-9

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DNA Replication

Edited By Stephen D. Bell, Indiana University, Bloomington; Marcel Méchali, Institute of Human Genetics, CNRS, Montpellier; Melvin L. DePamphilis, National Institutes of Health, Bethesda

© 2013 • 576 pp., illus. (88 4C, 33 B&W), appendices, index
Hardcover • $135 • ISBN 978-1-936113-48-4

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The Dawn of Human Genetics

By V.V. Babkov
Edited By James Schwartz; Translated from the Russian by Victor Fet

© 2013 • 775 pp., illus. (91 B&W ), index
Hardcover • $69 • ISBN 978-1-936113-70-5

In Russia, the initial euphoria of the Bolshevik leaders for a new socialist society ... combined with a commitment to a truly universal health care system, gave a huge boost to the emergence of both the eugenic and medical aspects of human genetics. The obstacles that proved so formidable to the successful launch of the field in the West—the lack of available data on the genealogy of diseases in families, the difficulty in getting a statistically significant number of identical twins to study, and the skepticism of the medical establishment—were all swept aside in the Soviet Union. In the 1920s ... the groundwork was laid for a uniquely Russian approach to medical genetics and (the foundation of) the world’s leading center for the study of the genetic basis of many diseases and human genetics in general. The immense success of the movement, which is little known even to Russians, is brought to life in V.V. Babkov’s The Dawn of Human Genetics, as is its dramatic and violent end, which resulted in the “liquidation” of many of the country’s finest biologists, as well as a major setback to the development of world science. Like many other promising ideas and projects that were born in the Soviet Union, this one was abruptly truncated and then virtually eradicated.

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The Endoplasmic Reticulum

Edited By Susan Ferro-Novick, University of California, San Diego; Tom A. Rapoport, Harvard Medical School; Randy Schekman, University of California at Berkeley

© 2013 • 336 pp., illus (61 4C, 9 B&W), index
Hardcover • $135 • ISBN 978-1-936113-82-8