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Speaking of Genetics: A Collection of Interviews

Edited By Jane Gitschier, Institute for Human Genetics, University of California, San Francisco

© 2011 • 259 pp., illus., further reading, index
Paperback • $19.00 • ISBN 978-1-936113-03-3

These 22 interviews were conducted by University of California Professor Jane Gitschier for publication in the scientific journal PLoS Genetics over the past 5 years. Here these interviews are presented as a single, stand-alone collection for the first time.

The collection makes a compelling read by capturing exhilarating moments of discovery on a wide range of genetic questions as recounted by the scientists themselves. We also hear from scientists whose careers have taken on a broader role—a University president, a master teacher, an author, the founder of a company, and an explorer. Further perspective is provided by several non-scientists whose work helps frame our understanding and practice of genetics; these include a judge, a reporter, an administrator, and an historian of science. Together, the interviews in this collection bring to life the practice and societal implications of contemporary genetics.

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Drosophila Neurobiology: A Laboratory Manual

Edited By Bing Zhang, University of Oklahoma; Marc R. Freeman, University of Massachusetts Medical School; Scott Waddell, University of Massachusetts Medical School

© 2010 • 534 pp., illus. (70 color, 43 b/w), appendix, index
Trim size: 8-1/2” x 10-7/8”
Paperback • $154.00 • ISBN 978-0-879699-05-5

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Drosophila Neurobiology: A Laboratory Manual

Edited By Bing Zhang, University of Oklahoma; Marc R. Freeman, University of Massachusetts Medical School; Scott Waddell, University of Massachusetts Medical School

© 2010 • 534 pp., illus. (70 color, 43 b/w), appendix, index
Trim size: 8-1/2” x 10-7/8”
Hardcover • $256.00 • ISBN 978-0-879699-04-8

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Generation and Interpretation of Morphogen Gradients

Edited By James Briscoe, MRC National Institute for Medical Research; Peter A. Lawrence, University of Cambridge, and MRC Laboratory of Molecular Biology; Jean-Paul Vincent, MRC National Institute for Medical Research

© 2010 • 308 pp., illus., index
Hardcover • $135 $33.75 • ISBN 978-0-879698-81-2

Signaling by diffusible morphogens, such as Hedgehog, Wingless, TGF-β, and various growth factors, is essential during embryogenesis. The establishment of concentration gradients of these morphogens is vital for developmental patterning, ensuring that distinct differentiated cell types appear in the right place and at the right time in forming tissues.

Written and edited by experts in the field, this volume explores how morphogen gradients are generated and interpreted during development. The contributors examine the regulation of morphogen synthesis, trafficking, and diffusion, as well as the complex webs of signaling mechanisms and transcriptional responses in recipient cells — whose fates are dictated by these morphogens. Including discussion of the roles of morphogen gradients in various tissues in organisms from yeast to humans, the volume is a vital reference for developmental biologists and cell biologists wishing to know how cell fate is determined during embryogenesis.

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C. elegans Atlas

By David H. Hall, Albert Einstein College of Medicine, New York; Zeynep F. Altun, Albert Einstein College of Medicine, New York

© 2008 • 348 pp., illus., appendix, index
Concealed wire binding • $128.00 $89.60 • ISBN 978-087969715-0

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C. elegans Atlas

By David H. Hall, Albert Einstein College of Medicine, New York; Zeynep F. Altun, Albert Einstein College of Medicine, New York

© 2008 • 348 pp., illus., appendix, index
Hardcover • $179.00 • ISBN 978-087969794-5

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Adult Neurogenesis
(Cold Spring Harbor Monograph Series 52)

Edited By Fred H. Gage, The Salk Institute for Biological Studies, San Diego, California; Gerd Kempermann, Center for Regenerative Therapies, Dresden, Germany; Hongjun Song, Johns Hopkins School of Medicine, Baltimore, Maryland

© 2008 • 673 pp., illus, index
Hardcover • $135 $67.50 • ISBN 978-087969784-6

The idea that the adult brain of mammals can generate new neurons has only recently been accepted by the scientific community, and research in this exciting area is now in full swing. Bringing together leading researchers in the field of adult neurogenesis, the 30 chapters in this monograph provide a valuable overview of this emerging field and lay the groundwork for future studies. Adult Neurogenesis includes discussions on neural stem cell biology; methods and models for studying adult neurogenesis; physiological and molecular processes and their control; related neurological diseases; and comparisons of neurogenesis in humans, birds, fish, and invertebrates. It will be of interest to all researchers in neurobiology as well as those in the medical field, as it has implications for understanding depression, epilepsy, and other psychiatric disorders.

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Clocks and Rhythms
(Cold Spring Harbor Symposia on Quantitative Biology LXXII)

Edited By Bruce Stillman, Cold Spring Harbor Laboratory; David Stewart, Cold Spring Harbor Laboratory; Terri Grodzicker, Cold Spring Harbor Laboratory

© 2007 • 674 pp., illus., indexes
(Hardcover edition includes online access; call for information and registration)
Hardcover • $310 $155.00 • ISBN 978-087969822-5

Based on presentations by world-renowned investigators at the 72nd annual Cold Spring Harbor Symposium on Quantitative Biology, this volume reviews the latest advances in biological clocks and rhythms. Topics include genetic and cellular studies aimed at characterizing circadian mechanisms; systems approaches to understanding physiological, endocrine, and neural networks; and models used for studying mental and physical cycles. A variety of normal and abnormal chronobiological patterns are discussed, including sleep, aging, migration, hibernation, seasonality, depression, and arrhythmias.

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Invertebrate Neurobiology
(Cold Spring Harbor Monograph Series 49)

Edited By Geoffrey North, Editor of Current Biology; Ralph J. Greenspan, The Neurosciences Institute, San Diego, California

© 2007 • 665 pp., illus., index
Hardcover • $135 $33.75 • ISBN 978-087969819-5

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An Introduction to Nervous Systems

By Ralph J. Greenspan, The Neurosciences Institute, San Diego, California

© 2007 • 172 pp., illus., bibliography, glossary, index
Paperback • $46.00 • ISBN 978-087969821-8