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Inspiring Science: Jim Watson and the Age of DNA

Edited By John Inglis, Cold Spring Harbor Laboratory; Joseph Sambrook, Peter MacCallum Cancer Centre; Jan A. Witkowski, Banbury Center, Cold Spring Harbor Laboratory

© 2003 • 503 pp., illus., bibliography, index
Hardcover • $37 $7.40 • ISBN 978-087969698-6

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Introduction to Protein-DNA Interactions: Structure, Thermodynamics, and Bioinformatics

By Gary D. Stormo, Ph.D.

© 2013 • 208 pp., illus. (78 4C, 5 B&W), index
Hardcover • $79 • ISBN 978-1-936113-49-1

One of the foundations of molecular biology is how the interactions of proteins with DNA control many aspects of gene expression. Since the mid-20th century, from discoveries of the lac repressor and operator and the competition between the cI and cro proteins for the same segment of DNA, we have learned an enormous amount about the interactions of proteins with DNA and their control of fundamental processes in the cell. Introduction to Protein–DNA Interactions: Structure, Thermodynamics, and Bioinformatics describes what we know about protein–DNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics and how each perspective informs the others. A particular emphasis is on how insights from experimental work can be translated into specific computational approaches to create a unified view of the field and a fuller understanding of protein–DNA interactions.

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Introduction to Protein-DNA Interactions: Structure, Thermodynamics, and Bioinformatics

By Gary D. Stormo, Ph.D.

© 2013 • 208 pp., illus. (78 4C, 5 B&W), index
Paperback • $45 • ISBN 978-1-936113-50-7

One of the foundations of molecular biology is how the interactions of proteins with DNA control many aspects of gene expression. Since the mid-20th century, from discoveries of the lac repressor and operator and the competition between the cI and cro proteins for the same segment of DNA, we have learned an enormous amount about the interactions of proteins with DNA and their control of fundamental processes in the cell. Introduction to Protein–DNA Interactions: Structure, Thermodynamics, and Bioinformatics describes what we know about protein–DNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics and how each perspective informs the others. A particular emphasis is on how insights from experimental work can be translated into specific computational approaches to create a unified view of the field and a fuller understanding of protein–DNA interactions.

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Invertebrate Neurobiology
(Cold Spring Harbor Monograph Series 49)

Edited By Geoffrey North, Editor of Current Biology; Ralph J. Greenspan, The Neurosciences Institute, San Diego, California

© 2007 • 665 pp., illus., index
Hardcover • $135 $33.75 • ISBN 978-087969819-5

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Is It in Your Genes? The Influence of Genes on Common Disorders and Diseases that Affect You and Your Family

By Philip R. Reilly, Interleukin Genetics

© 2004 • 304 pp., tables, further reading, index
Paperback • $21 $5.25 • ISBN 978-087969721-1

It is now clear that our risk of developing almost any disease is influenced by the genes with which we are born. One of the most important dividends of the Human Genome Project will be a much greater understanding of the influence of genes on disease and disorders in children (from asthma to autism) and adults (including heart disease, virtually all cancers, and Alzheimer's disease). The nature of genetic risks in families is becoming clearer and this book is written to help people understand them. Philip Reilly, a physician–geneticist, who has given hundreds of lectures on this subject, takes a user–friendly approach. Drawing on the many questions he has been asked (for example, “My sister has multiple sclerosis. Am I at an increased risk?”), Reilly discusses over 90 common conditions, diseases, and disorders, arranged from conception to old age. In frank, non–technical terms, he makes clear what is known and not known about the genetic factors and, if your risk is elevated, what you might be able to do about it. This book is a uniquely valuable resource for anyone seeking more information about a family’s disease heritage.

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Lab Dynamics: Management and Leadership Skills for Scientists, Second Edition

By Carl M. Cohen, Science Management Associates, Newton, Massachusetts; Suzanne L. Cohen, Science Management Associates, Newton, Massachusetts

© 2012 • 280 pp., illus., index
Hardcover • $59 $41.30 • ISBN 978-1-936113-78-1

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Lab Math: A Handbook of Measurements, Calculations, and Other Quantitative Skills for Use at the Bench

By Dany Spencer Adams, The Forsyth Institute

© 2003 • 275 pp., illus.
Concealed wire binding • $60.00 $42.00 • ISBN 978-087969634-4

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Lab Math: A Handbook of Measurements, Calculations, and Other Quantitative Skills for Use at the Bench, 2nd edition

By Dany Spencer Adams

Due September 2013 • 350pp. (approx.), illus., index
Concealed wire binding • $59 • ISBN 978-1-936113-71-2

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Lab Ref, Volume 1
A Handbook of Recipes, Reagents, and Other Reference Tools for Use at the Bench

Edited By Jane Roskams, University of British Columbia, Canada; Linda Rodgers, Cold Spring Harbor Laboratory

© 2002 • 272 pp., illus., appendices, index
Paperback • $25 • ISBN 978-1-936113-79-8

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Lab Ref, Volume 2
A Handbook of Recipes, Reagents, and Other Reference Tools for Use at the Bench

Edited By Albert S. Mellick, Cold Spring Harbor Laboratory, New York; Linda Rodgers, Cold Spring Harbor Laboratory, New York

© 2007 • 248 pp., illus., appendix, index
Concealed wire binding • $40.00 $28.00 • ISBN 978-087969815-7

Like its predecessor Lab Ref, Volume 1, this book is a handy benchtop source of recipes and information needed for common laboratory protocols. Lab Ref, Volume 2 contains recipes for procedures as diverse as RNA interference, imaging, proteomics, and quantitative nucleic acid analysis, and is organized by application for quick and easy reference. All recipes were derived from recent manuals published by Cold Spring Harbor Laboratory Press, and each recipe is cross-referenced to its manual of origin. Reference tables and charts are included. To meet the growing need for computational resources in the biology laboratory, Lab Ref, Volume 2 also has an expanded Web site section with sources for biological materials, databases for acquiring and annotating genomic and proteomic data, and links to downloadable software.

View two different sets of sample pages from the book here — and here —