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DNA Replication and Human Disease
(Cold Spring Harbor Monograph Series 47)

Edited By Melvin L. DePamphilis, National Institutes of Health

© 2006 • 814 pp., illus., appendices, index
Hardcover • $139 $34.75 • ISBN 978-087969766-2

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Pandora's Baby: How the First Test Tube Babies Sparked the Reproductive Revolution

By Robin Marantz Henig

© 2006 • 326 pp.
Paperback • $16.95 $8.47 • ISBN 978-087969809-6

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Genomes
(Cold Spring Harbor Monograph Series 46)

Edited By Hillary E. Sussman, Cold Spring Harbor Laboratory; Maria A. Smit, Cold Spring Harbor Laboratory

© 2006 • 475 pp., illus., index
Paperback • $59 $14.75 • ISBN 978-087969807-2

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Genomes
(Cold Spring Harbor Monograph Series 46)

Edited By Hillary E. Sussman, Cold Spring Harbor Laboratory; Maria A. Smit, Cold Spring Harbor Laboratory

© 2006 • 475 pp., illus., index
Hardcover • $139 $34.75 • ISBN 978-087969806-5

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Won for All: How the Drosophila Genome Was Sequenced

By Michael Ashburner

© 2006 • 107 pp., illus.
Hardcover • $19.95 $9.97 • ISBN 978-087969802-7

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The Dog and Its Genome
(Cold Spring Harbor Monograph Series 44)

Edited By Elaine A. Ostrander, National Human Genome Research Institute, NIH; Urs Giger, School of Veterinary Medicine, University of Pennsylvania, Philadelphia; Kerstin Lindblad-Toh, Broad Institute of MIT and Harvard

© 2006 • 584 pp., illus., index
Hardcover • $139 • ISBN 978-087969742-6

Dogs of different breeds can range remarkably in size, shape, and behavior, and yet they all carry essentially the same genome, making them a particularly fascinating model for genome plasticity. The recent release of the complete sequence of the dog genome provides an exciting new context in which to consider such variation. Twenty–five chapters written by experts in the field include various aspects of morphological and behavioral variation in dogs, their origins and domestication, and their unique value as a model system for many common but complex human diseases such as diabetes and cancer.

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Cell Biology of Addiction

Edited By Bertha K. Madras, Harvard Medical School; Christine M. Colvis, National Institute on Drug Abuse/NIH; Jonathan D. Pollock, National Institute on Drug Abuse/NIH; Joni L. Rutter, National Institute on Drug Abuse/NIH; David Shurtleff, National Institute on Drug Abuse/NIH; Mark von Zastrow, University of California, San Francisco

© 2006 • 465 pp., illus., appendices, index
Hardcover • $129 $32.25 • ISBN 978-087969753-2

This monograph, written by experts in the field, is devoted to the molecular analysis of addiction pathways in the brain. It provides an intensive overview of the fundamentals, state–of–the–art advances, and major gaps in the cell and molecular biology of drug addiction within the broader context of neuroscience. Addiction research is a branch of neuroscience and psychology. The emphasis in this book is on hard science and the market for it will be found among research investigators and grad students within the field of neuroscience. The research presented is not only applicable to the study of drug abuse and addiction, but has clear implications for clarifying mechanisms of learning and memory, neuroadaptation, perception, volitional behavior, motivation, reward, and other disciplines of neuroscience.

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Telomeres, Second Edition
(Cold Spring Harbor Monograph Series 45)

Edited By Titia de Lange, The Rockefeller University; Vicki Lundblad, The Salk Institute for Biological Sciences; Elizabeth Blackburn, University of California, San Francisco

© 2006 • 576 pp., illus., index
Paperback • $49 $9.80 • ISBN 978-087969810-2

An up–to–date survey of the current exciting state of telomere biology. Telomeres—specialized structures found at the ends of chromosomes— are essential for maintaining the integrity of chromosomes and their faithful duplication during cell division. Chapters in this volume cover telomere structure and function in a range of organisms, focusing on how they are maintained, their roles in cell division and gene expression, and how deficiencies in these structures contribute to cancers and other diseases and even aging.

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Telomeres, Second Edition
(Cold Spring Harbor Monograph Series 45)

Edited By Titia de Lange, The Rockefeller University; Vicki Lundblad, The Salk Institute for Biological Sciences; Elizabeth Blackburn, University of California, San Francisco

© 2006 • 576 pp., illus., index
Hardcover • $139 $27.80 • ISBN 978-087969734-1

An up–to–date survey of the current exciting state of telomere biology. Telomeres—specialized structures found at the ends of chromosomes— are essential for maintaining the integrity of chromosomes and their faithful duplication during cell division. Chapters in this volume cover telomere structure and function in a range of organisms, focusing on how they are maintained, their roles in cell division and gene expression, and how deficiencies in these structures contribute to cancers and other diseases and even aging.

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Landmark Papers in Yeast Biology

Edited By Patrick Linder, University of Geneva; David Shore, University of Geneva; Michael N. Hall, Biozentrum, University of Basel

© 2006 • 306 pp., index, CD
Printed hardcover • $99 $24.75 • ISBN 978-087969643-6

Yeast has been a preeminent experimental organism of genetic research for more than 50 years. Progress in the field has provided the conceptual framework that has driven experiments in many areas of biology. Landmark Papers in Yeast Biology consists of essays by prominent scientists on the context and significance of 71 carefully selected research papers, which are reprinted on the accompanying CD.  The papers include early, hard–to–find classics as well as more recent advances in areas such as signal transduction, membrane trafficking, protein turnover, and genomics. This collection has unique value for all scholars of yeast and could provide the foundation for a literature–based course on molecular cell biology.  As Jasper Rine notes in his eloquent introduction, the editors and contributors share the belief that “deep study of the agreed–on classics is the best training for learning how to recognize those contemporary papers worthy of our personal time....”