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Control and Regulation of Stem Cells
(Cold Spring Harbor Symposia on Quantitative Biology LXXIIl)

Edited By Bruce Stillman, Cold Spring Harbor Laboratory; David Stewart, Cold Spring Harbor Laboratory; Terri Grodzicker, Cold Spring Harbor Laboratory

© 2008 • 614 pp., illus., indexes
(Hardcover edition includes online access; call for information and registration)
Hardcover • $310 $155.00 • ISBN 978-087969861-4

Based on presentations by world-renowned investigators at the 73rd annual Cold Spring Harbor Symposium on Quantitative Biology, this volume reviews the latest advances in research on the control and regulation of stem cells. The topics covered include nuclear reprogramming, regulation of stem cell self-renewal and differentiation, the stem cell niche, and signaling and gene regulation in stem cells. Studies of embryonic stem cells and adult stem cells are covered, along with research shedding light on the roles of these cells in regeneration and cancer. 

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Correcting the Blueprint of Life: An Historical Account of the Discovery of DNA Repair Mechanisms

© 1997 • 210 pp., illus., index
Cloth • $27 $10.80 • ISBN 978-087969507-1

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Cystic Fibrosis: A Trilogy of Biochemistry, Physiology, and Therapy

Edited By John R. Riordan, The University of North Carolina at Chapel Hill; Richard C. Boucher, The University of North Carolina at Chapel Hill; Paul M. Quinton, University of California, San Diego School of Medicine

Due July 2013 • 400 pp.(approx.), illus. (approx. 37 4C; 11 B&W), index
Hardcover • $135 $101.25 • ISBN 978-1-936113-34-7

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Davenport’s Dream: 21^st Century Reflections on Heredity & Eugenics

Edited By Jan A. Witkowski, Cold Spring Harbor Laboratory; John R. Inglis, Cold Spring Harbor Laboratory

© 2008 • 490 pp., illus.
Hardcover • $55 $27.50 • ISBN 978-087969756-3

In 1911, the influential geneticist Charles Davenport published Heredity in Relation to Eugenics, advancing his ideas of how genetics would improve society in the 20th century. It became a college textbook and a foundation for the widespread eugenics movement in the United States. Nearly 100 years later, many of the issues raised by Davenport are again being debated, in different guises. In this new volume, prominent academics discuss themes from Davenport’s book—human genetic variation, mental illness, nature vs. nurture, human evolution—in a contemporary context. Davenport’s original book is reprinted along with the essays. This book will be useful to historians of science as well as those interested in the social implications of human genetics research—past, present, and future.

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The Dawn of Human Genetics

By V.V. Babkov
Edited By James Schwartz; Translated from the Russian by Victor Fet

© 2013 • 775 pp., illus. (91 B&W ), index
Hardcover • $69 • ISBN 978-1-936113-70-5

In Russia, the initial euphoria of the Bolshevik leaders for a new socialist society ... combined with a commitment to a truly universal health care system, gave a huge boost to the emergence of both the eugenic and medical aspects of human genetics. The obstacles that proved so formidable to the successful launch of the field in the West—the lack of available data on the genealogy of diseases in families, the difficulty in getting a statistically significant number of identical twins to study, and the skepticism of the medical establishment—were all swept aside in the Soviet Union. In the 1920s ... the groundwork was laid for a uniquely Russian approach to medical genetics and (the foundation of) the world’s leading center for the study of the genetic basis of many diseases and human genetics in general. The immense success of the movement, which is little known even to Russians, is brought to life in V.V. Babkov’s The Dawn of Human Genetics, as is its dramatic and violent end, which resulted in the “liquidation” of many of the country’s finest biologists, as well as a major setback to the development of world science. Like many other promising ideas and projects that were born in the Soviet Union, this one was abruptly truncated and then virtually eradicated.

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The Development of Drosophila melanogaster

Edited By Michael Bate, University of Cambridge; Alfonso Martinez Arias, University of Cambridge

© 1993 • 1,564 pp. (2-volume set), illus., indexes
Paperback • $256.00 • ISBN 978-087969899-7

The fruit fly Drosophila melanogaster offers the most powerful means of studying embryonic development in eukaryotes. New information from many different organ systems has accumulated rapidly in the past decade. This monograph, written by the most distinguished workers in the field, is the most authoritative and comprehensive synthesis of Drosophila developmental biology available and emphasizes the insights gained by molecular and genetic analysis. In two volumes, it is a lavishly illustrated, elegantly designed reference work illustrating principles of genetic regulation of embryogenesis that may apply to other eukaryotes.

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The Development of Human Gene Therapy
(Cold Spring Harbor Monograph Series 36)

Edited By Theodore Friedmann, University of California, San Diego

© 1999 • 729 pp., illus., color plates, index
Cloth • $140 $35.00 • ISBN 978-087969528-6

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DNA Replication

Edited By Stephen D. Bell, Indiana University, Bloomington; Marcel Méchali, Institute of Human Genetics, CNRS, Montpellier; Melvin L. DePamphilis, National Institutes of Health, Bethesda

© 2013 • 576 pp., illus. (88 4C, 33 B&W), appendices, index
Hardcover • $135 • ISBN 978-1-936113-48-4

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DNA Replication and Human Disease
(Cold Spring Harbor Monograph Series 47)

Edited By Melvin L. DePamphilis, National Institutes of Health

© 2006 • 814 pp., illus., appendices, index
Hardcover • $139 $34.75 • ISBN 978-087969766-2

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DNA Science: A First Course, Second Edition

By David A. Micklos, Dolan DNA Learning Center, Cold Spring Harbor Laboratory; Greg A. Freyer, Columbia University, New York

© 2003 • 575 pp., illus., appendices, index
Paperback • $40.00 • ISBN 978-1-936113-17-0