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George Beadle, An Uncommon Farmer: The Emergence of Genetics in the 20th Century

By Paul Berg, Stanford University School of Medicine; Maxine Singer, Carnegie Institution of Washington

© 2005 • 383 pp., illus., index
Paperback • $21 $10.50 • ISBN 978-087969763-1

George Beadle was a towering scientific figure whose work from the 1930s to 1960 marked the transition from classical genetics to the molecular era. Among other distinctions, he made the pivotal, Nobel Prize–winning discovery with Edward Tatum that the role of genes is to specify proteins. From 1946 to 1960 he led the Caltech Biology Division, rebuilding it to a powerhouse in molecular biology, and afterwards became a successful President of the University of Chicago. This is the first biography of a giant of genetics, written by two of the field's most distinguished contributors, Paul Berg and Maxine Singer.

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At the Bench: A Laboratory Navigator, Updated Edition

By Kathy Barker, The Institute for Systems Biology, Seattle

© 2005 • 465 pp., illus., appendices, index
Concealed wire binding • $61.00 • ISBN 978-087969708-2

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Mouse Phenotypes: A Handbook of Mutation Analysis

By Virginia E. Papaioannou, Columbia University College of Physicians and Surgeons; Richard R. Behringer, University of Texas MD Anderson Cancer Center

© 2005 • 235 pp., illus., appendices, index
Concealed wire binding • $91.00 • ISBN 978-087969640-5

The generation of mutant mice raises many questions about the best means of phenotypic analysis, breeding, and maintenance. The answers are now available from two experts with a wealth of detailed knowledge never previously assembled in one volume. Informal and highly practical, this handbook provides step–by–step methods for troubleshooting experiments, from the basics of gene targeting through the analysis of postnatal effects.

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The Writing Life of James D. Watson

By Errol C. Friedberg, University of Texas Southwestern Medical Center

© 2005 • 193 pp., illus., index
Hardcover • $26 $5.20 • ISBN 978-087969700-6

James Watson's fame as a scientist and research leader overshadows his considerable achievements as an innovator in the form and style of scientific communication. This book surveys Watson's books and essays from the perennially best–selling The Double Helix through his classic textbooks of the 1960s and 70s, polemics on ethical questions about genetic technology, to more recent works of autobiography.

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Epigenetics
(Cold Spring Harbor Symposia on Quantitative Biology LXIX)

Edited By Bruce Stillman, Cold Spring Harbor Laboratory; David Stewart, Cold Spring Harbor Laboratory

© 2004 • 532 pp., illus., index
(Paperback edition does not include online access)
Paperback • $126 $63.00 • ISBN 978-087969731-0

The importance of epigenetic regulation of gene expression, particularly in higher organisms, is now clear and the 2004 Cold Spring Harbor Annual Symposium provided many new examples as well as insights into the underlying mechanisms. The resulting volume—with over 60 papers from experts across the field—covers various aspects of nuclear organization and dynamics; genomic imprinting, chromosomal inactivation, and other examples of gene silencing; the histone and DNA modifications associated with these conditions; and the roles of RNA and protein regulators in establishing and maintaining these states.

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Epigenetics
(Cold Spring Harbor Symposia on Quantitative Biology LXIX)

Edited By Bruce Stillman, Cold Spring Harbor Laboratory; David Stewart, Cold Spring Harbor Laboratory

© 2004 • 532 pp., illus., index
(Hardcover edition includes online access; call for information and registration)
Hardcover • $310 $77.50 • ISBN 978-087969729-7

The importance of epigenetic regulation of gene expression, particularly in higher organisms, is now clear and the 2004 Cold Spring Harbor Annual Symposium provided many new examples as well as insights into the underlying mechanisms. The resulting volume—with over 60 papers from experts across the field—covers various aspects of nuclear organization and dynamics; genomic imprinting, chromosomal inactivation, and other examples of gene silencing; the histone and DNA modifications associated with these conditions; and the roles of RNA and protein regulators in establishing and maintaining these states.

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An Illustrated Chinese-English Guide for Biomedical Scientists

By James M. Samet; Weidong Wu; Yuh–Chin T. Huang; Xinchao Wang

© 2004 • 115 pp., illus., illustrations index
Paperback • $25 $6.25 • ISBN 978-087969648-1

The Illustrated Chinese–English Guide for Biomedical Scientists is intended to build confidence in the use of English scientific language.  The book lists terms that are in common use in science laboratories, translated into both simplified and complex Chinese. It also contains illustrations of equipment, labeled in both languages.

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An Illustrated Chinese-English Guide for Biomedical Scientists

By James M. Samet; Weidong Wu; Yuh–Chin T. Huang; Xinchao Wang

© 2004 • 115 pp., illus., illustrations index
Hardcover • $39 $9.75 • ISBN 978-087969701-3

The Illustrated Chinese–English Guide for Biomedical Scientists is intended to build confidence in the use of English scientific language.  The book lists terms that are in common use in science laboratories, translated into both simplified and complex Chinese. It also contains illustrations of equipment, labeled in both languages.

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Bioinformatics: Sequence and Genome Analysis, Second Edition

By David Mount, University of Arizona, Tucson

© 2004 • 665 pp., illus., appendices, index
Paperback • $95 • ISBN 978-087969712-9

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Gastrulation: From Cells to Embryo

Edited By Claudio D. Stern, University College London

© 2004 • 731 pp., illus., appendices, index
Printed hardcover • $158 $79.00 • ISBN 978-087969707-5

During gastrulation, tissue layers are formed and the overall body plan is established. This book is the definitive guide to this vitally important period in embryonic development, providing authoritative and up to date information that includes the first comprehensive interspecies comparison, cell movements and patterning events, the roles of individual genes and gene families, and the evolution of gastrulation.