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Emerging Model Organisms: A Laboratory Manual, Volume 1

© 2009 • 592 pp., illus., appendix, index
Paperback • $89 $44.50 • ISBN 978-087969872-0

Until recently, a small number of model organisms has been the focus of most research in molecular, cellular, and developmental biology. But in the last few years, due in part to increased interest in questions of evolution, technical advances in selectively altering gene expression patterns, and the reduced costs of genome sequencing, the range of organisms used for research is greatly expanding. Emerging Model Organisms, Volume 1, introduces the reader to this new generation of model organisms, providing a diverse catalog of potential species useful for extending research in new directions. In this volume leading experts provide chapters on 23 emerging model systems, ranging from bat and butterfly to cave fish and choanoflagellates; cricket and finch to quail, snail, and tomato. Subsequent releases of the Emerging Model Organisms series, already in preparation, will focus on additional species. Material is also available in CSH Protocols: www.cshprotocols.org/emo

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Emerging Model Organisms: A Laboratory Manual, Volume 1

© 2009 • 592 pp., illus., appendix, index
Hardcover • $158 $79.00 • ISBN 978-087969826-3

Until recently, a small number of model organisms has been the focus of most research in molecular, cellular, and developmental biology. But in the last few years, due in part to increased interest in questions of evolution, technical advances in selectively altering gene expression patterns, and the reduced costs of genome sequencing, the range of organisms used for research is greatly expanding. Emerging Model Organisms, Volume 1, introduces the reader to this new generation of model organisms, providing a diverse catalog of potential species useful for extending research in new directions. In this volume leading experts provide chapters on 23 emerging model systems, ranging from bat and butterfly to cave fish and choanoflagellates; cricket and finch to quail, snail, and tomato. Subsequent releases of the Emerging Model Organisms series, already in preparation, will focus on additional species. Material is also available in CSH Protocols: www.cshprotocols.org/emo

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Genetic Variation: A Laboratory Manual

Edited By Michael P. Weiner, RainDance Technologies, Inc., Guilford, Connecticut; Stacey B. Gabriel, The Broad Institute, Massachusetts Institute of Technology, Cambridge; J. Claiborne Stephens, Motif BioSciences, New York

© 2007 • 472 pp., illus., appendix, index
Paperback • $165 • ISBN 978-087969780-8

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Invertebrate Neurobiology
(Cold Spring Harbor Monograph Series 49)

Edited By Geoffrey North, Editor of Current Biology; Ralph J. Greenspan, The Neurosciences Institute, San Diego, California

© 2007 • 665 pp., illus., index
Hardcover • $135 $33.75 • ISBN 978-087969819-5

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Evolution

By Nicholas H. Barton, University of Edinburgh; Derek E.G. Briggs, Yale University; Jonathan A. Eisen, University of California, Davis; David B. Goldstein, Duke University Medical Center; Nipam H. Patel, University of California, Berkeley

© 2007 • 833 pp., color illus., glossary, index
Price subject to change
Hardcover • $113.00 • ISBN 978-087969684-9

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An Introduction to Nervous Systems

By Ralph J. Greenspan, The Neurosciences Institute, San Diego, California

© 2007 • 172 pp., illus., bibliography, glossary, index
Paperback • $46.00 • ISBN 978-087969821-8

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An Introduction to Nervous Systems

By Ralph J. Greenspan, The Neurosciences Institute, San Diego, California

© 2007 • 172 pp., illus., bibliography, glossary, index
Hardcover • $67.00 $33.50 • ISBN 978-087969757-0

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Epigenetics
(Cold Spring Harbor Symposia on Quantitative Biology LXIX)

Edited By Bruce Stillman, Cold Spring Harbor Laboratory; David Stewart, Cold Spring Harbor Laboratory

© 2004 • 532 pp., illus., index
(Paperback edition does not include online access)
Paperback • $126 $63.00 • ISBN 978-087969731-0

The importance of epigenetic regulation of gene expression, particularly in higher organisms, is now clear and the 2004 Cold Spring Harbor Annual Symposium provided many new examples as well as insights into the underlying mechanisms. The resulting volume—with over 60 papers from experts across the field—covers various aspects of nuclear organization and dynamics; genomic imprinting, chromosomal inactivation, and other examples of gene silencing; the histone and DNA modifications associated with these conditions; and the roles of RNA and protein regulators in establishing and maintaining these states.

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Epigenetics
(Cold Spring Harbor Symposia on Quantitative Biology LXIX)

Edited By Bruce Stillman, Cold Spring Harbor Laboratory; David Stewart, Cold Spring Harbor Laboratory

© 2004 • 532 pp., illus., index
(Hardcover edition includes online access; call for information and registration)
Hardcover • $310 $77.50 • ISBN 978-087969729-7

The importance of epigenetic regulation of gene expression, particularly in higher organisms, is now clear and the 2004 Cold Spring Harbor Annual Symposium provided many new examples as well as insights into the underlying mechanisms. The resulting volume—with over 60 papers from experts across the field—covers various aspects of nuclear organization and dynamics; genomic imprinting, chromosomal inactivation, and other examples of gene silencing; the histone and DNA modifications associated with these conditions; and the roles of RNA and protein regulators in establishing and maintaining these states.

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The Genome of Homo sapiens
(Cold Spring Harbor Symposia on Quantitative Biology LXVIII)

By Bruce Stillman, Cold Spring Harbor Laboratory; David Stewart, Cold Spring Harbor Laboratory

© 2003 • 544 pp., illus., appendices, index
(Paperback edition does not include online access)
Paperback • $126 $25.20 • ISBN 978-087969710-5

The Human Genome Project was completed in 2003, 50 years after the discovery of the structure of DNA and 17 years after an influential debate at the annual Cold Spring Harbor Laboratory Symposium about the Project’s feasibility. The 2003 Symposium was dedicated to examining what has been learned so far from the human genome sequence. This book contains over sixty contributions from the world’s leaders in this field and covers genome structure and evolution, methods of data analysis, lessons from species comparison, and the application of sequence data to the understanding of disease.

Purchasers of the hard cover edition of this book are entitled to access to the Symposia website at www.cshl-symposium.org. The site contains the full text of the written communications from the 2003 Symposium and the Symposia held in 1998 through 2002 (Volumes LXIII–LXVII). Subscribers to the site also gain access to archive photographs and selected papers from the 60–year history of the Annual Symposium.