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Imaging in Neuroscience: A Laboratory Manual

Edited By Fritjof Helmchen, Brain Research Institute, University of Zurich, Switzerland; Arthur Konnerth, Institute for Neurosciences, Technical University Munich, Germany; Series Editor, Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 1084 pp., illus., index
Paperback • $200.00 $140.00 • ISBN 978-0-879699-38-3

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Imaging in Neuroscience: A Laboratory Manual

Edited By Fritjof Helmchen, Brain Research Institute, University of Zurich, Switzerland; Arthur Konnerth, Institute for Neurosciences, Technical University Munich, Germany; Series Editor, Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 1084 pp., illus., index
Hardcover • $287.00 $200.90 • ISBN 978-0-879699-37-6

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Imaging in Developmental Biology: A Laboratory Manual

Edited By James Sharpe, EMBL-CRG Systems Biology Unit, Barcelona, Spain; Rachel Wong, University of Washington; Series Editor, Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 883 pp., illus., index
Paperback • $169.00 $118.30 • ISBN 978-0-879699-40-6

New imaging technologies have revolutionized the study of developmental biology. Where researchers once struggled to connect events at static timepoints, imaging tools now offer the ability to visualize the dynamic form and function of molecules, cells, tissues, and whole embryos throughout the entire developmental process. Imaging in Developmental Biology: A Laboratory Manual, a new volume in Cold Spring Harbor Laboratory Press’ Imaging series, presents a comprehensive set of essential visualization methods. The manual features primers on live imaging of a variety of standard model organisms including C. elegans, Drosophila, zebrafish, Xenopus, avian species, and mouse. Further techniques are organized by the level of visualization they provide, from cells to tissues and organs to whole embryos. Methods range from the basics of labeling cells to cutting-edge protocols for high-speed imaging, optical projection tomography, and digital scanned laser light-sheet fluorescence. Imaging has become a required methodology for developmental biologists, and Imaging in Developmental Biology: A Laboratory Manual provides the detailed explanations and instructions for mastering these necessary techniques.

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Imaging in Developmental Biology: A Laboratory Manual

Edited By James Sharpe, EMBL-CRG Systems Biology Unit, Barcelona, Spain; Rachel Wong, University of Washington; Series Editor, Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 883 pp., illus., index
Hardcover • $246.00 $172.20 • ISBN 978-0-879699-39-0

New imaging technologies have revolutionized the study of developmental biology. Where researchers once struggled to connect events at static timepoints, imaging tools now offer the ability to visualize the dynamic form and function of molecules, cells, tissues, and whole embryos throughout the entire developmental process. Imaging in Developmental Biology: A Laboratory Manual, a new volume in Cold Spring Harbor Laboratory Press’ Imaging series, presents a comprehensive set of essential visualization methods. The manual features primers on live imaging of a variety of standard model organisms including C. elegans, Drosophila, zebrafish, Xenopus, avian species, and mouse. Further techniques are organized by the level of visualization they provide, from cells to tissues and organs to whole embryos. Methods range from the basics of labeling cells to cutting-edge protocols for high-speed imaging, optical projection tomography, and digital scanned laser light-sheet fluorescence. Imaging has become a required methodology for developmental biologists, and Imaging in Developmental Biology: A Laboratory Manual provides the detailed explanations and instructions for mastering these necessary techniques.

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Imaging: A Laboratory Manual

Edited By Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 952 pp., illus. (182 color, 97 b/w), appendices, index
Trim size: 8-1/2” x 10-7/8”
Paperback • $169.00 $118.30 • ISBN 978-0-879699-36-9

In recent years, imaging has rapidly become a tremendously valuable approach in nearly every field of biological research. Finding the right method and optimizing it for data collection can be a daunting process, even for an established imaging laboratory. Imaging: A Laboratory Manual is the cornerstone of a new laboratory manual series, designed as an essential guide for investigators who need these visualization techniques. This first volume is meant as a general reference for all fields, and describes the theory and practice of a wide array of imaging methods. From the basic chapters on optics, equipment and labeling to detailed explanations of advanced, cutting-edge methods like PALM, STORM, light sheet and high speed microscopy, Imaging: A Laboratory Manual is a vital resource for the modern biology laboratory.

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Imaging: A Laboratory Manual

Edited By Rafael Yuste, Howard Hughes Medical Institute, Columbia University

© 2011 • 952 pp., illus. (182 color, 97 b/w), appendices, index
Trim size: 8-1/2” x 10-7/8”
Hardcover • $246.00 $172.20 • ISBN 978-0-879699-35-2

In recent years, imaging has rapidly become a tremendously valuable approach in nearly every field of biological research. Finding the right method and optimizing it for data collection can be a daunting process, even for an established imaging laboratory. Imaging: A Laboratory Manual is the cornerstone of a new laboratory manual series, designed as an essential guide for investigators who need these visualization techniques. This first volume is meant as a general reference for all fields, and describes the theory and practice of a wide array of imaging methods. From the basic chapters on optics, equipment and labeling to detailed explanations of advanced, cutting-edge methods like PALM, STORM, light sheet and high speed microscopy, Imaging: A Laboratory Manual is a vital resource for the modern biology laboratory.

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Live Cell Imaging: A Laboratory Manual, Second Edition

Edited By Robert D. Goldman, Feinberg School of Medicine Northwestern University; Jason R. Swedlow, The University of Dundee; David L. Spector, Cold Spring Harbor Laboratory

© 2010 • 736 pp., illus., appendix, index
Paperback • $169.00 $118.30 • ISBN 978-0-879698-93-5

The second edition of Live Cell Imaging: A Laboratory Manual expands upon and extends the collection of established and evolving methods for studying dynamic changes in living cells and organisms presented in the well-known first edition. There are 16 new chapters and the 21 updated chapters in this new edition. They include advances in atomic force microscopy, structured illumination microscopy and other 3-D approaches, as well as imaging in single cells in animals and in plants. New analytical options include live high-throughput/high-content screening in mammalian cells and computational analysis of live cell data. The manual presents hands-on techniques as well as background material, and can serve as a text in advanced courses. The first section covers principles and fundamental issues of detection and imaging; the second provides detailed protocols for imaging live systems.

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Live Cell Imaging: A Laboratory Manual, Second Edition

Edited By Robert D. Goldman, Feinberg School of Medicine Northwestern University; Jason R. Swedlow, The University of Dundee; David L. Spector, Cold Spring Harbor Laboratory

© 2010 • 736 pp., illus., appendix, index
Hardcover • $246.00 $172.20 • ISBN 978-0-879698-92-8

The second edition of Live Cell Imaging: A Laboratory Manual expands upon and extends the collection of established and evolving methods for studying dynamic changes in living cells and organisms presented in the well-known first edition. There are 16 new chapters and the 21 updated chapters in this new edition. They include advances in atomic force microscopy, structured illumination microscopy and other 3-D approaches, as well as imaging in single cells in animals and in plants. New analytical options include live high-throughput/high-content screening in mammalian cells and computational analysis of live cell data. The manual presents hands-on techniques as well as background material, and can serve as a text in advanced courses. The first section covers principles and fundamental issues of detection and imaging; the second provides detailed protocols for imaging live systems.

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Mouse Hematology: A Laboratory Manual

By Michael P. McGarry, Department of Biochemistry and Molecular Biology, Mayo Clinic Arizona; Cheryl A. Protheroe, Department of Biochemistry and Molecular Biology, Mayo Clinic Arizona; James J. Lee, Department of Biochemistry and Molecular Biology, Mayo Clinic Arizona

© 2010 • 100 pp., illus., appendix, index; poster; DVD
Hardcover • $169.00 • ISBN 978-0-879698-85-0

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Lab Ref, Volume 2
A Handbook of Recipes, Reagents, and Other Reference Tools for Use at the Bench

Edited By Albert S. Mellick, Cold Spring Harbor Laboratory, New York; Linda Rodgers, Cold Spring Harbor Laboratory, New York

© 2007 • 248 pp., illus., appendix, index
Concealed wire binding • $40.00 $28.00 • ISBN 978-087969815-7

Like its predecessor Lab Ref, Volume 1, this book is a handy benchtop source of recipes and information needed for common laboratory protocols. Lab Ref, Volume 2 contains recipes for procedures as diverse as RNA interference, imaging, proteomics, and quantitative nucleic acid analysis, and is organized by application for quick and easy reference. All recipes were derived from recent manuals published by Cold Spring Harbor Laboratory Press, and each recipe is cross-referenced to its manual of origin. Reference tables and charts are included. To meet the growing need for computational resources in the biology laboratory, Lab Ref, Volume 2 also has an expanded Web site section with sources for biological materials, databases for acquiring and annotating genomic and proteomic data, and links to downloadable software.

View two different sets of sample pages from the book here — and here —