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Transcriptional Regulation in Eukaryotes: Concepts, Strategies, and Techniques, Second Edition

Transcriptional Regulation in Eukaryotes: Concepts, Strategies, and Techniques, Second Edition

By Michael F. Carey, University of California, Los Angeles; Craig L. Peterson, University of Massachusetts Medical School, Worcester; Stephen T. Smale, University of California, Los Angeles

© 2009 • 620 pp., appendix, index
Hardcover • $246.00 • ISBN 978-087969777-8

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Transcriptional Regulation in Eukaryotes: Concepts, Strategies, and Techniques, Second Edition

Transcriptional Regulation in Eukaryotes: Concepts, Strategies, and Techniques, Second Edition

By Michael F. Carey, University of California, Los Angeles; Craig L. Peterson, University of Massachusetts Medical School, Worcester; Stephen T. Smale, University of California, Los Angeles

© 2009 • 620 pp., appendix, index
Paperback • $169.00 • ISBN 978-087969762-4

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Translational Control in Biology and Medicine

Translational Control in Biology and Medicine
(Cold Spring Harbor Monograph Series 48)

Edited By Michael B. Mathews, UMDNJ-New Jersey Medical School, Newark, New Jersey; Nahum Sonenberg, McGill University, Montreal, Canada; John W.B. Hershey, University of California, Davis

© 2007 • 934 pp., illus., index
Hardcover • $139 $34.75 • ISBN 978-087969767-9

The new edition of this successful monograph has been both updated and broadened. Since the previous (second) edition was published in 2000, the structures of the bacterial and eukaryotic ribosomes have been published, advancing our basic understanding of translation and mechanisms involving protein and RNA regulators. In addition, as the title indicates, this edition has a new focus on the role of translational control in human development and disease. This book, with 30 chapters written by experts in the field, is essential reading for anyone interested in the process of translation, its regulation, and how its failure can be the cause of disease.

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Type 1 Diabetes

Type 1 Diabetes

Edited By Jeffrey A. Bluestone, University of California at San Francisco; Mark A. Atkinson, University of Florida, College of Medicine; Peter R. Arvan, University of Michigan Health System

© 2012 • 305 pp., illus., index
Hardcover • $135 • ISBN 978-1-936113-21-7

Type 1 diabetes, also known as juvenile-onset or insulin-dependent diabetes mellitus (IDDM), is caused by destruction of insulin-producing β cells in the pancreas by the body’s immune system. It affects hundreds of thousands of individuals worldwide, requiring regular insulin injections to control blood glucose levels and avoid severe consequences of glucose dysregulation. Written by experts in the field, this book provides a detailed examination of our understanding of the disease process and its causes, as well as genetic risk factors, animal models of diabetes, and new treatment strategies that are being developed.

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