Cold Spring Harbor Lab Press Proteins and Proteomics

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Proteins and Proteomics


More INFO on this Product	The Endoplasmic Reticulum Edited By Susan Ferro-Novick, University of California, San Diego; Tom A. Rapoport, Harvard Medical School; Randy Schekman, University of California at Berkeley © 2013 • 336 pp., illus (61 4C, 9 B&W), index Hardcover • $135 • ISBN 978-1-936113-82-8

More INFO on this Product	Proteomics: A Cold Spring Harbor Laboratory Course Manual By Andrew J. Link, Vanderbilt University School of Medicine, Nashville, Tennessee; Joshua LaBaer, Harvard University School of Medicine © 2009 • 228 pp., illus., appendices, index Paperback • $96.00 • ISBN 978-087969787-7

More INFO on this Product	Proteomics: A Cold Spring Harbor Laboratory Course Manual By Andrew J. Link, Vanderbilt University School of Medicine, Nashville, Tennessee; Joshua LaBaer, Harvard University School of Medicine © 2009 • 228 pp., illus., appendices, index Hardcover • $154.00 • ISBN 978-087969793-8

More INFO on this Product	Basic Methods in Protein Purification and Analysis: A Laboratory Manual Edited By Richard J. Simpson, Joint ProteomicS Laboratory (JPSL) of the Ludwig Institute for Cancer Research and the Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia; Peter D. Adams, Fox Chase Cancer Center, Philadelphia; Erica A. Golemis, Fox Chase Cancer Center, Philadelphia © 2009 • 436 pp., illus., appendices, index Paperback • $97 • ISBN 978-087969-867-6 Understanding how proteins function is an essential part of many biological research endeavors. The complexity and sheer number of proteins in a cell are impediments to identifying proteins of interest or purifying proteins for function and structure analysis. Thus, reducing the complexity of a protein sample or in some cases purifying a protein to homogeneity is necessary. The latest manual in the Basic Methods series contains a collection of convenient and easy to use protein purification protocols along with a sampling of dependable methods for assessing protein–protein interactions. The protocols are supported by background information to assist researchers in understanding how the purification methods work and how to optimize and troubleshoot the methods. The collection of essential methods found in Basic Methods in Protein Purification and Analysis is mainly drawn from the popular manuals Proteins and Proteomics, Purifying Proteins for Proteomics, and Protein–Protein Interactions, 2nd Ed. In addition to protocols for purification using gel electrophoresis and column chromatography, this book contains tested methods for preparing cellular and subcellular extracts—a critical and often neglected step in successful protein purification. Rounding out the manual are methods for characterizing protein–protein interactions, an extensive appendix of essential methods for quantifying protein concentration, stabilizing and storing proteins, concentrating proteins, and immunoblotting. Finally, there is a new chapter on a method complementary to gel electrophoresis and chromatography: in silico analysis of genomic and proteomic databases.

More INFO on this Product	Basic Methods in Protein Purification and Analysis: A Laboratory Manual Edited By Richard J. Simpson, Joint ProteomicS Laboratory (JPSL) of the Ludwig Institute for Cancer Research and the Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia; Peter D. Adams, Fox Chase Cancer Center, Philadelphia; Erica A. Golemis, Fox Chase Cancer Center, Philadelphia © 2009 • 436 pp., illus., appendices, index Hardcover • $162.00 • ISBN 978-087969868-3 Understanding how proteins function is an essential part of many biological research endeavors. The complexity and sheer number of proteins in a cell are impediments to identifying proteins of interest or purifying proteins for function and structure analysis. Thus, reducing the complexity of a protein sample or in some cases purifying a protein to homogeneity is necessary. The latest manual in the Basic Methods series contains a collection of convenient and easy to use protein purification protocols along with a sampling of dependable methods for assessing protein–protein interactions. The protocols are supported by background information to assist researchers in understanding how the purification methods work and how to optimize and troubleshoot the methods. The collection of essential methods found in Basic Methods in Protein Purification and Analysis is mainly drawn from the popular manuals Proteins and Proteomics, Purifying Proteins for Proteomics, and Protein–Protein Interactions, 2nd Ed. In addition to protocols for purification using gel electrophoresis and column chromatography, this book contains tested methods for preparing cellular and subcellular extracts—a critical and often neglected step in successful protein purification. Rounding out the manual are methods for characterizing protein–protein interactions, an extensive appendix of essential methods for quantifying protein concentration, stabilizing and storing proteins, concentrating proteins, and immunoblotting. Finally, there is a new chapter on a method complementary to gel electrophoresis and chromatography: in silico analysis of genomic and proteomic databases.

More INFO on this Product	Lab Ref, Volume 2 A Handbook of Recipes, Reagents, and Other Reference Tools for Use at the Bench Edited By Albert S. Mellick, Cold Spring Harbor Laboratory, New York; Linda Rodgers, Cold Spring Harbor Laboratory, New York © 2007 • 248 pp., illus., appendix, index Concealed wire binding • ~~$40.00~~ $28.00 • ISBN 978-087969815-7 Like its predecessor Lab Ref, Volume 1, this book is a handy benchtop source of recipes and information needed for common laboratory protocols. Lab Ref, Volume 2 contains recipes for procedures as diverse as RNA interference, imaging, proteomics, and quantitative nucleic acid analysis, and is organized by application for quick and easy reference. All recipes were derived from recent manuals published by Cold Spring Harbor Laboratory Press, and each recipe is cross-referenced to its manual of origin. Reference tables and charts are included. To meet the growing need for computational resources in the biology laboratory, Lab Ref, Volume 2 also has an expanded Web site section with sources for biological materials, databases for acquiring and annotating genomic and proteomic data, and links to downloadable software. View two different sets of sample pages from the book here — and here —

More INFO on this Product	Protein-Protein Interactions: A Molecular Cloning Manual, Second Edition Edited By Erica A. Golemis, Fox Chase Cancer Center, Philadelphia; Peter D. Adams, Fox Chase Cancer Center, Philadelphia © 2005 • 938 pp., illus., index Paperback • ~~$173~~ $34.60 • ISBN 978-087969723-5 This is an updated edition of a manual that provides a thorough collection of the technical and theoretical issues involved in the study of protein associations, including standard methods, biophysical approaches, and, in a final section, a collection of computational methods for integrating and analyzing interactions.

More INFO on this Product	Protein-Protein Interactions: A Molecular Cloning Manual, Second Edition Edited By Erica A. Golemis, Fox Chase Cancer Center, Philadelphia; Peter D. Adams, Fox Chase Cancer Center, Philadelphia © 2005 • 938 pp., illus., index Hardcover • ~~$231~~ $46.20 • ISBN 978-087969722-8 This is an updated edition of a manual that provides a thorough collection of the technical and theoretical issues involved in the study of protein associations, including standard methods, biophysical approaches, and, in a final section, a collection of computational methods for integrating and analyzing interactions.

More INFO on this Product	The Inside Story: DNA to RNA to Protein Edited By Jan Witkowski, Cold Spring Harbor Laboratory © 2005 • 382 pp., illus., index Paperback • ~~$29~~ $14.50 • ISBN 978-087969750-1

More INFO on this Product	Prion Biology and Diseases, Second Edition (Cold Spring Harbor Monograph Series 41) Edited By Stanley B. Prusiner, University of California, San Francisco © 2004 • 1,050 pp., illus., color plates, glossary, appendix, index Hardcover • ~~$147~~ $29.40 • ISBN 978-087969693-1 This volume is a new edition of the most authoritative book on Prion Biology, first published in 1999 and edited by the Nobel Prize–winning founder of the field. This expanded edition has been completely updated, and includes chapters on therapeutics, and diagnostic methods and approaches.

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