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Immunoreceptor Signaling

Edited By Lawrence E. Samelson, National Institutes of Health; Andrey Shaw, Washington University School of Medicine

© 2011 • 282 pp., illus. (49 color, 7 b/w), index
Trim size: 7” x 10”
Hardcover • $135 $33.75 • ISBN 978-0-879698-96-6

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Incurable: A Life after Diagnosis

By Charles Harris

© 2011 • 280 pp., illus.
Hardcover • $31.00 • ISBN 978-1-936113-10-1

In March 2009, during a routine medical exam, Charles Harris learned that he had incurable cancer. Although a private man, he began a blog to keep family and friends current on his progress, and found a wider audience. From the blog was born Incurable, an account of a man’s struggle to live vibrantly and with courage in the face of a fatal illness. An entrepreneur and investor by profession, Charles Harris writes about living and dying, friendship and fellowship, sports and wine, race horses and recessions. His style is optimistic, direct, humorous, and companionable. Readers will find his voice brave, inspirational, and an eloquent reminder that an understanding of cancer remains an urgent goal in biomedicine. Proceeds from this book will be used by the Harris family in support of cancer research.

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The Inside Story: DNA to RNA to Protein

Edited By Jan Witkowski, Cold Spring Harbor Laboratory

© 2005 • 382 pp., illus., index
Paperback • $29 $14.50 • ISBN 978-087969750-1

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Inspiring Science: Jim Watson and the Age of DNA

Edited By John Inglis, Cold Spring Harbor Laboratory; Joseph Sambrook, Peter MacCallum Cancer Centre; Jan A. Witkowski, Banbury Center, Cold Spring Harbor Laboratory

© 2003 • 503 pp., illus., bibliography, index
Hardcover • $37 $7.40 • ISBN 978-087969698-6

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Introduction to Protein-DNA Interactions: Structure, Thermodynamics, and Bioinformatics

By Gary D. Stormo, Ph.D.

© 2013 • 208 pp., illus. (78 4C, 5 B&W), index
Hardcover • $79 • ISBN 978-1-936113-49-1

One of the foundations of molecular biology is how the interactions of proteins with DNA control many aspects of gene expression. Since the mid-20th century, from discoveries of the lac repressor and operator and the competition between the cI and cro proteins for the same segment of DNA, we have learned an enormous amount about the interactions of proteins with DNA and their control of fundamental processes in the cell. Introduction to Protein–DNA Interactions: Structure, Thermodynamics, and Bioinformatics describes what we know about protein–DNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics and how each perspective informs the others. A particular emphasis is on how insights from experimental work can be translated into specific computational approaches to create a unified view of the field and a fuller understanding of protein–DNA interactions.

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Introduction to Protein-DNA Interactions: Structure, Thermodynamics, and Bioinformatics

By Gary D. Stormo, Ph.D.

© 2013 • 208 pp., illus. (78 4C, 5 B&W), index
Paperback • $45 • ISBN 978-1-936113-50-7

One of the foundations of molecular biology is how the interactions of proteins with DNA control many aspects of gene expression. Since the mid-20th century, from discoveries of the lac repressor and operator and the competition between the cI and cro proteins for the same segment of DNA, we have learned an enormous amount about the interactions of proteins with DNA and their control of fundamental processes in the cell. Introduction to Protein–DNA Interactions: Structure, Thermodynamics, and Bioinformatics describes what we know about protein–DNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics and how each perspective informs the others. A particular emphasis is on how insights from experimental work can be translated into specific computational approaches to create a unified view of the field and a fuller understanding of protein–DNA interactions.

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Invertebrate Neurobiology
(Cold Spring Harbor Monograph Series 49)

Edited By Geoffrey North, Editor of Current Biology; Ralph J. Greenspan, The Neurosciences Institute, San Diego, California

© 2007 • 665 pp., illus., index
Hardcover • $135 $33.75 • ISBN 978-087969819-5

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Is It in Your Genes? The Influence of Genes on Common Disorders and Diseases that Affect You and Your Family

By Philip R. Reilly, Interleukin Genetics

© 2004 • 304 pp., tables, further reading, index
Paperback • $21 $5.25 • ISBN 978-087969721-1

It is now clear that our risk of developing almost any disease is influenced by the genes with which we are born. One of the most important dividends of the Human Genome Project will be a much greater understanding of the influence of genes on disease and disorders in children (from asthma to autism) and adults (including heart disease, virtually all cancers, and Alzheimer's disease). The nature of genetic risks in families is becoming clearer and this book is written to help people understand them. Philip Reilly, a physician–geneticist, who has given hundreds of lectures on this subject, takes a user–friendly approach. Drawing on the many questions he has been asked (for example, “My sister has multiple sclerosis. Am I at an increased risk?”), Reilly discusses over 90 common conditions, diseases, and disorders, arranged from conception to old age. In frank, non–technical terms, he makes clear what is known and not known about the genetic factors and, if your risk is elevated, what you might be able to do about it. This book is a uniquely valuable resource for anyone seeking more information about a family’s disease heritage.

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Lab Dynamics: Management and Leadership Skills for Scientists, Second Edition

By Carl M. Cohen, Science Management Associates, Newton, Massachusetts; Suzanne L. Cohen, Science Management Associates, Newton, Massachusetts

© 2012 • 280 pp., illus., index
Hardcover • $59 $41.30 • ISBN 978-1-936113-78-1

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Lab Math: A Handbook of Measurements, Calculations, and Other Quantitative Skills for Use at the Bench

By Dany Spencer Adams, The Forsyth Institute

© 2003 • 275 pp., illus.
Concealed wire binding • $60.00 $42.00 • ISBN 978-087969634-4