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Laboratory Research Notebook

© 2005 • 50 pp.
Paperback • £8.00 • ISBN 978-087969760-0

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Laboratory Research Notebook

© 2005 • 100 pp.
Hardcover • £6.00 • ISBN 978-087969759-4

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Landmark Papers in Yeast Biology

Edited By Patrick Linder, University of Geneva; David Shore, University of Geneva; Michael N. Hall, Biozentrum, University of Basel

© 2006 • 306 pp., index, CD
Printed hardcover • £16.00 £4.00 • ISBN 978-087969643-6

Yeast has been a preeminent experimental organism of genetic research for more than 50 years. Progress in the field has provided the conceptual framework that has driven experiments in many areas of biology. Landmark Papers in Yeast Biology consists of essays by prominent scientists on the context and significance of 71 carefully selected research papers, which are reprinted on the accompanying CD.  The papers include early, hard–to–find classics as well as more recent advances in areas such as signal transduction, membrane trafficking, protein turnover, and genomics. This collection has unique value for all scholars of yeast and could provide the foundation for a literature–based course on molecular cell biology.  As Jasper Rine notes in his eloquent introduction, the editors and contributors share the belief that “deep study of the agreed–on classics is the best training for learning how to recognize those contemporary papers worthy of our personal time....”

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Life Illuminated: Selected Papers from Cold Spring Harbor
Volume 2, 1972–1994

Edited By Jan A. Witkowski, Cold Spring Harbor Laboratory, New York; Alexander Gann, Cold Spring Harbor Laboratory, New York; Joseph F. Sambrook, Peter MacCallum Cancer Institute, East Melbourne, Australia

© 2008 • 242 pp., illustrations from original articles, indexes, CD
Hardcover • £12.00 £6.00 • ISBN 978-087969804-1

This book is the second volume of an intellectual history of the science done at CSHL (the first volume, Illuminating Life, showed that genetics became the dominant theme of research at CSH by as early as 1904). The appointment of James Watson as Director of the Laboratory in 1968 set off the explosive research development at CSH, as he recruited widely and wisely teams of investigators with diverse scientific interests. From this collection of papers, presented in full on the accompanying CD, several themes emerge: the characterization and exploitation of mobile genetic elements; the mechanics of DNA replication and regulation of the cell cycle; the behavior and internal architecture of cells; how viruses induce tumors; the discovery of cancer genes; the characteristics of neurons; and the invention of techniques that make possible further progress. Each theme is introduced in the context of the science of the time, and each paper has a commentary by, in most cases, one of its authors. Life Illuminated is a story of scientific innovation and achievement, told in the words of the investigators themselves.

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Live Cell Imaging: A Laboratory Manual, Second Edition

Edited By Robert D. Goldman, Feinberg School of Medicine Northwestern University; Jason R. Swedlow, The University of Dundee; David L. Spector, Cold Spring Harbor Laboratory

© 2010 • 736 pp., illus., appendix, index
Hardcover • £155.00 £108.50 • ISBN 978-0-879698-92-8

The second edition of Live Cell Imaging: A Laboratory Manual expands upon and extends the collection of established and evolving methods for studying dynamic changes in living cells and organisms presented in the well-known first edition. There are 16 new chapters and the 21 updated chapters in this new edition. They include advances in atomic force microscopy, structured illumination microscopy and other 3-D approaches, as well as imaging in single cells in animals and in plants. New analytical options include live high-throughput/high-content screening in mammalian cells and computational analysis of live cell data. The manual presents hands-on techniques as well as background material, and can serve as a text in advanced courses. The first section covers principles and fundamental issues of detection and imaging; the second provides detailed protocols for imaging live systems.

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Live Cell Imaging: A Laboratory Manual, Second Edition

Edited By Robert D. Goldman, Feinberg School of Medicine Northwestern University; Jason R. Swedlow, The University of Dundee; David L. Spector, Cold Spring Harbor Laboratory

© 2010 • 736 pp., illus., appendix, index
Paperback • £107.00 £74.90 • ISBN 978-0-879698-93-5

The second edition of Live Cell Imaging: A Laboratory Manual expands upon and extends the collection of established and evolving methods for studying dynamic changes in living cells and organisms presented in the well-known first edition. There are 16 new chapters and the 21 updated chapters in this new edition. They include advances in atomic force microscopy, structured illumination microscopy and other 3-D approaches, as well as imaging in single cells in animals and in plants. New analytical options include live high-throughput/high-content screening in mammalian cells and computational analysis of live cell data. The manual presents hands-on techniques as well as background material, and can serve as a text in advanced courses. The first section covers principles and fundamental issues of detection and imaging; the second provides detailed protocols for imaging live systems.

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Mammalian Development: Networks, Switches, and Morphogenetic Processes

Edited By Patrick P.L. Tam, Children’s Medical Research Institute; W. James Nelson, Stanford University; Janet Rossant, The Hospital for Sick Children

© 2013 • 520 pp., illus. (120 4C, 21 B&W), index
Hardcover • £98 • ISBN 978-1-936113-24-8

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The Mammary Gland as an Experimental Model

Edited By Mina J. Bissell, Lawrence Berkeley National Laboratory; Kornelia Polyak, Harvard Medical School; Jeffrey M. Rosen, Baylor College of Medicine

© 2011 • 325 pp., illus. (54 color, 5 b/w), index
Hardcover • £85.00 • ISBN 978-0-879699-06-2

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Manipulating the Mouse Embryo: A Laboratory Manual (Third Edition)

By Andras Nagy, Samuel Lunenfeld Research Institute; Marina Gertsenstein, Samuel Lunenfeld Research Institute; Kristina Vintersten, European Molecular Biology Laboratory; Richard Behringer, University of Texas M.D. Anderson Cancer Center

© 2003 • 764 pp., illus., appendices, index
Paperback • £107.00 • ISBN 978-087969591-0

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Max Perutz and the Secret of Life

By Georgina Ferry

© 2007 • 352 pp., illus., glossary, index
All orders from outside of the United States, Europe, and China must be directed to Chatto and Windus, an imprint of Random House at www.randomhouse.co.uk/chatto/

Don’t miss the new podcast and online slideshow featuring Georgina Ferry discussing her book and Max Perutz.