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Addiction

Edited By R. Christopher Pierce, University of Pennsylvania; Paul J. Kenny, The Scripps Research Institute

© 2013 • 368 pp., illus (30 4C and 25 B&W), index
Hardcover • £85 • ISBN 978-1-936113-47-7

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Parkinson's Disease

Edited By Serge Przedborski, Columbia University

© 2012 • 406 pp., illus. (36 4C images and 19 B&W), index
Hardcover • £85.00 • ISBN 978-1-936113-32-3

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Angiogenesis: Biology and Pathology

Edited By Michael Klagsbrun, Children's Hospital Boston; Patricia D'Amore, Schepens Eye Research Institute

© 2011 • 522 pp., illus. (62 4C and 11 B&W), index
Hardcover • £85.00 • ISBN 978-1-936113-43-9

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The Strongest Boy in the World: How Genetic Information is Reshaping Our Lives, Updated and Expanded Edition

By Philip R. Reilly

© 2008 • 300 pp., illus., bibliography, index
Paperback • £10.00 • ISBN 978-087969943-7

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Concerning the Origin of Malignant Tumours

By Theodor Boveri; Translated and annotated by Sir Henry Harris

© 2008 • 82 pp.
Paperback • £16.00 • ISBN 978-087969788-4

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Molecular Biology of Aging
(Cold Spring Harbor Monograph Series 51)

Edited By Leonard P. Guarente, Massachusetts Institute of Technology, Cambridge; Linda Partridge, University College London, UK; Douglas C. Wallace, University of California, Irvine

© 2008 • 610 pp., illus., index
Hardcover • £85.00 • ISBN 978-087969824-9

Research into the causes of aging, and strategies to delay that process, have gained much ground and attention in recent years. This volume covers the major threads in the molecular genetics of aging, including genes that regulate aging, causes of aging, evolutionary theories of aging, and the relationship between diet and aging. Among specific topics covered are calorie restriction, mitochondria, sirtuins, telomeres, stem cells, and cancer. Each chapter is written by one or more leaders in the field, and the book presents the current status of this exciting research area and provides an invaluable source of information in a single volume.

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Gene Transfer: Delivery and Expression of DNA and RNA, A Laboratory Manual

Edited By Theodore Friedmann, University of California, San Diego; John Rossi, Beckman Research Institute of the City of Hope, Duarte, California

© 2007 • 793 pp., illus., appendix, index
Paperback • £26.00 £6.50 • ISBN 978-087969765-5

Understanding gene function and regulation requires rigorous testing in live cells and organisms. Recent advances have provided a variety of new strategies for delivering DNA and RNA into cells and probing their expression, as well as new clinical applications that rely upon the introduction of genetic material. The vast number of available techniques for clinical and laboratory research often makes selecting the optimal method a difficult process. Gene Transfer: Delivery and Expression of DNA and RNA provides the first comprehensive guide to technical approaches for delivering nucleic acids into cells and organisms and of ensuring (even manipulating) appropriate expression. The detailed, step-by-step protocols cover a variety of methods, both well established and newly evolving. These include viral and nonviral methods of gene delivery, transgenic approaches, strategies for the regulation of transgene expression, and modification of the host response. The introductory matter to each chapter includes concise technical and theoretical discussions with considerations for selection of the appropriate system and strategies for delivery.

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Gene Transfer: Delivery and Expression of DNA and RNA, A Laboratory Manual

Edited By Theodore Friedmann, University of California, San Diego; John Rossi, Beckman Research Institute of the City of Hope, Duarte, California

© 2007 • 793 pp., illus., appendix, index
Hardcover • £42.00 £10.50 • ISBN 978-087969764-8

Understanding gene function and regulation requires rigorous testing in live cells and organisms. Recent advances have provided a variety of new strategies for delivering DNA and RNA into cells and probing their expression, as well as new clinical applications that rely upon the introduction of genetic material. The vast number of available techniques for clinical and laboratory research often makes selecting the optimal method a difficult process. Gene Transfer: Delivery and Expression of DNA and RNA provides the first comprehensive guide to technical approaches for delivering nucleic acids into cells and organisms and of ensuring (even manipulating) appropriate expression. The detailed, step-by-step protocols cover a variety of methods, both well established and newly evolving. These include viral and nonviral methods of gene delivery, transgenic approaches, strategies for the regulation of transgene expression, and modification of the host response. The introductory matter to each chapter includes concise technical and theoretical discussions with considerations for selection of the appropriate system and strategies for delivery.

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Pandora's Baby: How the First Test Tube Babies Sparked the Reproductive Revolution

By Robin Marantz Henig

© 2006 • 326 pp.
Paperback • £5.00 £2.50 • ISBN 978-087969809-6

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Is It in Your Genes? The Influence of Genes on Common Disorders and Diseases that Affect You and Your Family

By Philip R. Reilly, Interleukin Genetics

© 2004 • 304 pp., tables, further reading, index
Paperback • £3.00 £0.75 • ISBN 978-087969721-1

It is now clear that our risk of developing almost any disease is influenced by the genes with which we are born. One of the most important dividends of the Human Genome Project will be a much greater understanding of the influence of genes on disease and disorders in children (from asthma to autism) and adults (including heart disease, virtually all cancers, and Alzheimer's disease). The nature of genetic risks in families is becoming clearer and this book is written to help people understand them. Philip Reilly, a physician–geneticist, who has given hundreds of lectures on this subject, takes a user–friendly approach. Drawing on the many questions he has been asked (for example, “My sister has multiple sclerosis. Am I at an increased risk?”), Reilly discusses over 90 common conditions, diseases, and disorders, arranged from conception to old age. In frank, non–technical terms, he makes clear what is known and not known about the genetic factors and, if your risk is elevated, what you might be able to do about it. This book is a uniquely valuable resource for anyone seeking more information about a family’s disease heritage.