More INFO on
this Product

Binding and Kinetics for Molecular Biologists

By James A. Goodrich, University of Colorado, Boulder; Jennifer F. Kugel, University of Colorado, Boulder

© 2007 • 182 pp., illus., appendices, index
Concealed wire binding • $61.00 • ISBN 978-087969736-5

This handbook offers a practical guide to the principles of quantitative analysis in biological experiments. The material is primarily aimed at working molecular biologists, but the scope and clarity of presentation make it equally suitable as an introduction for students. Topics covered range from the basics—such as measuring the concentrations of macromolecules—through considerations of binding constants and the kinetics of molecular interactions. The book ends with a thorough consideration of data analysis.

More INFO on
this Product

Experimental Design for Biologists

By David J. Glass, M.D., Novartis Institutes for Biomedical Research, Cambridge, Massachusetts

© 2007 • 206 pp., illus., index
Hardcover • $37.00 $25.90 • ISBN 978-087969735-8

More INFO on
this Product

Lab Ref, Volume 2
A Handbook of Recipes, Reagents, and Other Reference Tools for Use at the Bench

Edited By Albert S. Mellick, Cold Spring Harbor Laboratory, New York; Linda Rodgers, Cold Spring Harbor Laboratory, New York

© 2007 • 248 pp., illus., appendix, index
Concealed wire binding • $40.00 $28.00 • ISBN 978-087969815-7

Like its predecessor Lab Ref, Volume 1, this book is a handy benchtop source of recipes and information needed for common laboratory protocols. Lab Ref, Volume 2 contains recipes for procedures as diverse as RNA interference, imaging, proteomics, and quantitative nucleic acid analysis, and is organized by application for quick and easy reference. All recipes were derived from recent manuals published by Cold Spring Harbor Laboratory Press, and each recipe is cross-referenced to its manual of origin. Reference tables and charts are included. To meet the growing need for computational resources in the biology laboratory, Lab Ref, Volume 2 also has an expanded Web site section with sources for biological materials, databases for acquiring and annotating genomic and proteomic data, and links to downloadable software.

View two different sets of sample pages from the book here — and here —

More INFO on
this Product

Basic Methods in Microscopy
Protocols and Concepts from Cells: A Laboratory Manual

By David L. Spector, Cold Spring Harbor Laboratory; Robert D. Goldman, Northwestern University Medical School, Chicago

© 2006 • 382 pp., illus., index
Paperback • $97.00 • ISBN 978-087969751-8

Imaging has become a vital tool for researchers in all aspects of biology. Recent advances in microscope technology, labeling techniques and gene and protein manipulation methods have led to breakthroughs in our understanding of biological processes. In order to take advantage of these techniques, biologists need to understand the fundamental techniques of microscopy. The methods found here, drawn from the popular laboratory standard manual Cells: A Laboratory Manual, provide a solid course in the basics of using the microscope in a biology laboratory.

Basic Methods in Microscopy provides an essential guide to light microscopy, fluorescence microscopy, confocal microscopy, multiphoton microscopy and electron microscopy, preparation of tissues and cells, labeling of specimens and analysis of cellular events.

This manual is an important tool for any biology researcher employing imaging as a research method.

More INFO on
this Product

Protein-Protein Interactions: A Molecular Cloning Manual, Second Edition

Edited By Erica A. Golemis, Fox Chase Cancer Center, Philadelphia; Peter D. Adams, Fox Chase Cancer Center, Philadelphia

© 2005 • 938 pp., illus., index
Paperback • $173 $34.60 • ISBN 978-087969723-5

This is an updated edition of a manual that provides a thorough collection of the technical and theoretical issues involved in the study of protein associations, including standard methods, biophysical approaches, and, in a final section, a collection of computational methods for integrating and analyzing interactions.

More INFO on
this Product

Protein-Protein Interactions: A Molecular Cloning Manual, Second Edition

Edited By Erica A. Golemis, Fox Chase Cancer Center, Philadelphia; Peter D. Adams, Fox Chase Cancer Center, Philadelphia

© 2005 • 938 pp., illus., index
Hardcover • $231 $46.20 • ISBN 978-087969722-8

This is an updated edition of a manual that provides a thorough collection of the technical and theoretical issues involved in the study of protein associations, including standard methods, biophysical approaches, and, in a final section, a collection of computational methods for integrating and analyzing interactions.

More INFO on
this Product

Laboratory Research Notebook

© 2005 • 50 pp.
Paperback • $12.00 $2.40 • ISBN 978-087969760-0

More INFO on
this Product

Laboratory Research Notebook

© 2005 • 100 pp.
Hardcover • $9.00 • ISBN 978-087969759-4

More INFO on
this Product

Methods in Yeast Genetics: A Cold Spring Harbor Laboratory Course Manual, 2005 Edition

By David C. Amberg, Upstate Medical University, Syracuse; Daniel J. Burke, University of Virginia Medical Center, Charlottesville; Jeffrey N. Strathern, National Cancer Institute

© 2005 • 230 pp., illus., index
Paperback • $96.00 • ISBN 978-087969728-0

“Methods in Yeast Genetics” is a course that has been offered annually at Cold Spring Harbor Laboratory for the last thirty years. This is an updated edition of the course manual, which provides a set of teaching experiments, along with protocols and recipes for the standard techniques and reagents used in the study of yeast biology. Since the last edition of the manual was published (2000), revolutionary advances in genomics and proteomics technologies have had a significant impact on the field. This updated edition reflects these advances, and also includes new techniques involving vital staining, visualization of Green Fluorescent Protein, new drug resistance markers, high-copy suppression, Tandem Affinity Protein tag protein purification, gene disruption by double-fusion polymerase chain reaction, and many other recent developments.

More INFO on
this Product

At the Bench: A Laboratory Navigator, Updated Edition

By Kathy Barker, The Institute for Systems Biology, Seattle

© 2005 • 465 pp., illus., appendices, index
Concealed wire binding • $61.00 • ISBN 978-087969708-2