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Learning and Memory


Book Series:  A Cold Spring Harbor Perspectives in Biology Collection
Subject Area(s):  Cognition and BehaviorNeurobiology

Edited by Eric R. Kandel, MD, Columbia University; Yadin Dudai, PhD, The Weizmann Institute of Science; Mark R. Mayford, PhD, The Scripps Research Institute

Download a Free Excerpt from Learning and Memory:

Preface
Index


© 2016 • 389 pages, illustrated (65 color, 12 B&W), index
Hardcover • $135 108.00 (click here to price in UK Pounds)
ISBN  978-1-621820-91-8
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Description

We learn and remember information by modifying synaptic connections in the neuronal networks of our brain. Depending on the type of information being stored, these changes occur in different regions and different circuits of the brain. The underlying circuit mechanisms are beginning to be understood. These mechanisms are capable of storing or reconstructing memories for periods ranging up to a lifetime, but they are also error-prone, as memories can be distorted or lost.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines important aspects of the neurobiology of learning and memory. Contributors review the various types of memory and the anatomical architectures and specialized cells involved. The induction of synaptic and cell-wide changes during memory encoding, the transcriptional and translational programs required for memory stabilization, the molecular signals that actively maintain memories, and the activation of neural ensembles during memory retrieval are comprehensively covered.

The authors also discuss model organisms and state-of-the-art technologies used to elucidate these processes. This volume will serve as a valuable reference for all neurobiologists and biomedical scientists as well as for cognitive and computational neuroscientists wishing to explore the remarkable phenomena of learning and memory.

Contents

Preface
SECTION I: ENCODING
Conscious and Unconscious Memory Systems
Larry R. Squire and Adam J.O. Dede
Nonassociative Learning in Invertebrates
John H. Byrne and Robert D. Hawkins
Motor Learning and the Cerebellum
Chris I. De Zeeuw and Michiel M. Ten Brinke
The Striatum: Where Skills and Habits Meet
Ann M. Graybiel and Scott T. Grafton
Associative Learning in Invertebrates
Robert D. Hawkins and John H. Byrne
The Origins and Organization of Vertebrate Pavlovian Conditioning
Michael S. Fanselow and Kate M. Wassum
Molecular Genetic Strategies in the Study of Corticohippocampal Circuits
Christopher C. Angelakos and Ted Abel
The Corticohippocampal Circuit, Synaptic Plasticity, and Memory
Jayeeta Basu and Steven A. Siegelbaum
SECTION II: CONSOLIDATION
The Regulation of Transcription in Memory Consolidation
Cristina M. Alberini and Eric R. Kandel
Structural Components of Synaptic Plasticity and Memory Consolidation
Craig H. Bailey, Eric R. Kandel, and Kristen M. Harris
Memory Consolidation
Larry R. Squire, Lisa Genzel, John T. Wixted, and Richard G. Morris
SECTION III: MAINTENANCE, RECONSOLIDATION, AND RETRIEVAL
The Role of Functional Prion-Like Proteins in the Persistence of Memory
Kausik Si and Eric R. Kandel
Reconsolidation and the Dynamic Nature of Memory
Karim Nader
Memory Retrieval in Mice and Men
Aya Ben-Yakov, Yadin Dudai, and Mark R. Mayford
Place Cells, Grid Cells, and Memory
May-Britt Moser, Dave C. Rowland, and Edvard I. Moser
Working Memory: Maintenance, Updating, and the Realization of Intentions
Lars Nyberg and Johan Eriksson
SECTION IV: NOVEL APPROACHES
Large-Scale Fluorescence Calcium-Imaging Methods for Studies of Long-Term Memory in Behaving Mammals
Pablo Jercog, Thomas Rogerson, and Mark J. Schnitzer
Exploring Memory Representations with Activity-Based Genetics
Mark Mayford and Leon Reijmers
Noninvasive Functional and Anatomical Imaging of the Human Medial Temporal Lobe
Thackery I. Brown, Bernhard P. Staresina, and Anthony D. Wagner
Index