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Cell Biology of Bacteria

Subject Area(s):  Cell BiologyMolecular BiologyMicrobiology

Edited by Lucy Shapiro, Stanford University; Richard M. Losick, Harvard University

View an excerpt from the book here

© 2011 • 264 pp., illus. (58 color, 17 b/w), index
Trim size: 7" x 10"
Hardcover • $135 54.00 (click here to price in UK Pounds)
ISBN  978-0-879699-07-9
You save: 60%

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Until recently, bacteria were frequently depicted as “bags of enzymes” in which proteins and DNA were distributed relatively haphazardly compared with animal and plant cells. Research performed over the past decade has revolutionized our understanding of bacterial cells, however, revealing that they are in fact highly organized and contain numerous subcompartments.

Written and edited by experts in the field, this volume includes contributions discussing the three dimensional organization of the bacterial cell, various subcellular structures found in bacteria, membrane bounded organelles such as magnetosomes, and the organization of the cell membrane. Other chapters examine the recently identified bacterial cytoskeletal filaments which turn out to be remarkably similar to their eukaryotic counterparts as well as the roles of these filaments in morphogenesis and cytokinesis.

Also covered are the extraordinary organization of the bacterial genome and the dynamic mechanisms that couple its replication and partitioning at cell division. In addition, the book reviews the various different multicellular structures bacteria can form, such as biofilms, along with new imaging techniques that promise to reveal even more about their subcellular machinery. It is thus of interest to microscopists and biochemists, as well as all microbiologists and cell biologists interested in how bacteria and other prokaryotes function.


Bacterial Chromosome Organization and Segregation
Esteban Toro and Lucy Shapiro
Synchronization of Chromosome Dynamics and Cell Division in Bacteria
Martin Thanbichler
The Structure and Function of Bacterial Actin Homologs
Joshua W. Shaevitz and Zemer Gitai
Protein Subcellular Localization in Bacteria
David Z. Rudner and Richard Losick
Poles Apart: Prokaryotic Polar Organelles and Their Spatial Regulation
Clare L. Kirkpatrick and Patrick H. Viollier
The Bacterial Cell Envelope
Thomas J. Silhavy, Daniel Kahne, and Suzanne Walker
Cell Biology of Prokaryotic Organelles
Dorothee Murat, Meghan Byrne, and Arash Komeili
Bacterial Nanomachines: The Flagellum and Type III Injectisome
Marc Erhardt, Keiichi Namba, and Kelly T. Hughes
Membrane-associated DNATransport Machines
Briana Burton and David Dubnau
Myxobacteria, Polarity, and Multicellular Morphogenesis
Dale Kaiser, Mark Robinson, and Lee Kroos
Cyanobacterial Heterocysts
Krithika Kumar, Rodrigo A. Mella-Herrera, and James W. Golden
Daniel López, Hera Vlamakis, and Roberto Kolter
Electron Cryotomography
Elitza I. Tocheva, Zhuo Li, and Grant J. Jensen
Single-Molecule and Superresolution Imaging in Live Bacteria Cells
Julie S. Biteen and W.E. Moerner
Automated Quantitative Live Cell Fluorescence Microscopy
Michael Fero and Kit Pogliano

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