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Bone: A Regulator of Physiology

Book Series:  A Cold Spring Harbor Perspectives in Medicine Collection
Subject Area(s):  Human Biology and Disease

Edited by Gerard Karsenty, Columbia University Medical Center; David T. Scadden, Harvard Medical School

Due April 2018 • 200 pages (approx.), illustrated, index
Hardcover • $135 (click here to price in UK Pounds)
ISBN  978-1-621822-20-2

  •     Description    
  •     Contents    


Bone plays far more than just a structural role in our bodies. It actively communicates with our brains and other organs, releasing and responding to signaling molecules that regulate numerous biological processes. This book reviews the classical functions of bone as well as exciting new work that has revealed novel aspects of its biology.


“But Why Bone?”
Gerard Karsenty
Bone Remodeling and the Microbiome
Roberto Pacifici
Regulation of Bone Metabolism by Sex Steroids
Sundeep Khosla and David G. Monroe
Bone Mineralization
Monzur Murshed
Regulation of Bone Remodelng by Parathyroid Hormone
Marc N. Wein and Henry M. Kronenberg
Hiroshi Takayanagi and Kazuo Okamoto
The Biology of Bone Metastasis
Mark Esposito, Theresa Guise, and Yibin Kang
Biology of FGF23: From Physiology to Pathology
Marie Courbebaisse and Beate Lanske
Multiple Myeloma and Bone: The Fatal Interaction
Silvia Marino and G. David Roodman
The Bone Marrow Microenvironment in Health and Myeloid Malignancy
Marta Galán-Díez, Álvaro Cuesta-Domínguez, and Stavroula Kousteni
Neural Regulation of Bone Marrow
Paul Frenette
Biology of Bone: The Vasculature of the Skeletal System
Emma C. Watson and Ralf H. Adams
Michael P. Whyte
Regulation of Energy Metabolism by Bone-Derived Hormones
Paula Mera, Mathieu Ferron, and Ioanna Mosialou