HIV: From Biology to Prevention and Treatment

Click to Enlarge				HIV: From Biology to Prevention and Treatment Subject Area(s): Human Biology and Disease; Immunology and Vaccines; Viruses Edited by Frederic D. Bushman, University of Pennsylvania School of Medicine; Gary J. Nabel, NIAID, National Institutes of Health; Ronald Swanstrom, University of North Carolina at Chapel Hill Download Free Excerpts from HIV: From Biology to Prevention and Treatment: Download Preface and Contents Download Index

				© 2011 • 572 pp., illus. (95 4C and 4 B&W), index Hardcover • ~~$135~~ 94.50 ISBN 978-1-936113-40-8 You save: 30% You will receive free shipping on this item at checkout. Free shipping offer applies to direct website purchases by individual U.S. and Canada customers only.

Description Contents Description The worldwide AIDS epidemic makes research on HIV, the disease processes it induces, and potential HIV therapies among the most critical in biomedical science. Furthermore, the basic biology of HIV infections provides a model for a more general understanding of retroviruses and their hosts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine provides a comprehensive review of HIV research, covering everything from the pathogenesis of HIV infection to prevention. Contributors explore the origins and evolution of HIV, the HIV replication cycle, host–virus interactions, host immune responses, and HIV transmission. Vaccines, cell and gene therapies, antiretroviral drugs, microbicides, and behavioral strategies for the treatment and prevention of HIV infections are also explored. This volume, which includes discussions of social and economic factors that affect HIV transmission and treatment, is an essential reference for virologists, cell and molecular biologists, and immunologists, as well as epidemiologists, physicians, and other public health professionals. Contents Preface Origins of HIV and the AIDS Pandemic Paul M. Sharp and Beatrice H. Hahn HIV REPLICATION HIV: Cell Binding and Entry Craig B. Wilen, John C. Tilton, and Robert W. Doms HIV-1 Reverse Transcription Wei-Shau Hu and Stephen H. Hughes HIV DNA Integration Robert Craigie and Frederic D. Bushman Transcriptional and Posttranscriptional Regulation of HIV-1 Gene Expression Jonathan Karn and C. Martin Stoltzfus HIV Assembly, Budding, and Maturation Wesley I. Sundquist and Hans-Georg Kraüsslich HIV Restriction Factors and Mechanisms of Evasion Michael H. Malim and Paul D. Bieniasz HIV TRANSMISSION AND PATHOGENESIS HIV Transmission George M. Shaw and Eric Hunter HIV-1 Pathogenesis: The Virus Ronald Swanstrom and John Coffin HIV Pathogenesis: Dynamics and Genetics of Viral Populations and Infected Cells John Coffin and Ronald Swanstrom HIV Pathogenesis: The Host A.A. Lackner, Michael M. Lederman, and Benigno Rodriguez The Antibody Response against HIV-1 Julie Overbaugh and Lynn Morris The T-Cell Response to HIV Bruce Walker and Andrew McMichael Innate Immune Control of HIV Mary Carrington and Galit Alter HIV Latency Robert F. Siliciano and Warner C. Greene HIV-1-Related Central Nervous System Disease: Current Issues in Pathogenesis, Diagnosis, and Treatment Serena Spudich and Francisco González-Scarano Nonpathogenic Simian Immunodeficiency Virus Infections Nichole R. Klatt, Guido Silvestri, and Vanessa Hirsch THERAPY AND PREVENTION HIV-1 Antiretroviral Drug Therapy Eric J. Arts and Daria J. Hazuda Novel Cell and Gene Therapies for HIV James A. Hoxie and Carl H. June The HIV-1 Epidemic: Low- to Middle-Income Countries Yiming Shao and Carolyn Williamson The HIV Epidemic: High-Income Countries Sten H. Vermund and Andrew J. Leigh-Brown Host Genes Important to HIV Replication and Evolution Amalio Telenti and Welkin E. Johnson Vaccine Design for CD8 T Lymphocyte Responses Richard A. Koup and Daniel C. Douek Rational Design of Vaccines to Elicit Broadly Neutralizing Antibodies to HIV-1 Peter D. Kwong, John R. Mascola, and Gary J. Nabel Lessons in Nonhuman Primate Models for AIDS Vaccine Research: From Minefields to Milestones Jeffrey D. Lifson and Nancy L. Haigwood Human Immunodeficiency Virus Vaccine Trials Robert J. O’Connell, Jerome H. Kim, Lawrence Corey, and Nelson L. Michael Microbicides: Topical Prevention against HIV Robin J. Shattock and Zeda Rosenberg HIV Prevention by Oral Preexposure Prophylaxis Walid Heneine and Angela Kashuba Behavioral and Biomedical Combination Strategies for HIV Prevention Linda-Gail Bekker, Chris Beyrer, and Thomas C. Quinn Index

HIV: From Biology to Prevention and Treatment

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