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Genes & Development

Edited By T. Grodzicker, Cold Spring Harbor Laboratory Press

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© 2019 • ISSN 0890-9369; Volume 33 includes full online access
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January - December 2019, 24 semimonthly issues
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Genes & Development publishes high-quality research papers of broad general interest and biological significance in the areas of molecular biology, molecular genetics, and related fields. G&D publishes two research formats; Research papers and short Research Communications, in addition to Review Articles and Perspectives. G&D consistently ranks in the top 10 among primary research journals in all fields of science.
This journal is published in association with The Genetics Society.
Subscription to the print journal includes full access to the online edition (online-only subscriptions are available upon request).

 
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Genome Research

Edited By Hillary Sussman, Cold Spring Harbor Laboratory Press; Aravinda Chakravarti, Johns Hopkins School of Medicine; Richard Gibbs, Baylor College of Medicine; Eric Green, Bethesda, MD; Richard Myers, HudsonAlpha Institute for Biotechnology; William Pavan, Derwood, MD

Online Features: Internet edition – Genome Research Online at Stanford University Libraries' HighWire Press; Electronic supplementary material – auxiliary data available only via the journal's online edition

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© 2019 • ISSN: 1088-9051; Volume 29 includes full online access
FREE TRIAL ACCESS offer for libraries! Contact cironek@cshl.edu.
January - December 2019, 12 monthly issues
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In August 1995, Cold Spring Harbor Laboratory Press began publication of a new, monthly, international, peer-reviewed journal, Genome Research. The journal focuses on genome studies in all species, and presents research that provides or aids in genome-based analyses of biological processes. The journal represents a nexus point where genomic information, applications, and technology come together with biological information to create a more global understanding of all biological systems.

Among the research considered by the journal are novel reports on gene discovery, comparative genome analyses, evolution studies, informatics, genome structure and function, technological innovations and applications, statistical and mathematical methods, cutting-edge genetic and physical mapping and DNA sequencing, and other reports that present data where sequence information is used to address biological concerns.

New data in these areas are published as research papers in the form of articles and letters, or methods and resource reports that provide novel information on methodologies or resources that will be of interest to a broad readership. Complete data sets are presented electronically on the journal's web site where appropriate. The journal also provides review articles, perspectives, and Insight/Outlook articles, which presents commentary on the latest advances published both here and elsewhere, placing such progress in its broader biological context.

Subscription to the print journal includes full access to the online edition (online-only subscriptions are not available).

 
 

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Genes & Development [Journal]
Learning & Memory [Journal]
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Learning & Memory

Edited By John H. Byrne, University of Texas School of Medicine

Online Features: Internet edition – Learning & Memory Online at Stanford University Libraries' HighWire Press

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© 2019 • ISSN 1549-5485; Volume 26; includes full online access
FREE TRIAL ACCESS offer for libraries! Contact cironek@cshl.edu.
January - December 2019, 12 online  issues
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Learning & Memory is the journal of choice for interdisciplinary studies on synaptic plasticity, learning, and memory. Until now, there has been no one journal devoted to this area of study and no dominant journal that demands attention by serious workers in the area, regardless of specialty. Spanning molecules, cells, systems, and behavior, L&M considers research using approaches from cellular and molecular biology, genetics, biochemistry, computational neuroscience, neurophysiology, neuropharmacology, neuroanatomy, behavior, and cognition. Learning & Memory provides a forum for these investigations in the form of original research papers, review articles, and brief communications.

 
 

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Genes & Development [Journal]
Genome Research [Journal]
RNA [Journal]
 
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CSH Perspectives in Medicine

Online Features: CSH Perspectives in Medicine – CSH Perspectives in Medicine at Stanford University Libraries' HighWire Press

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© 2019 • ISSN: 2157-1422; Volume 9 includes full online access
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January - December 2019, 12 monthly issues
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Cold Spring Harbor Perspectives in Medicine is a new online publication covering everything from the molecular and cellular bases of disease to translational medicine and new therapeutic strategies. Each issue offers reviews on different aspects of a variety of diseases and the tissues they affect. The contributions are written by experts in each field and commissioned as Subject Collections by a board of eminent scientists and physicians, all of whom are acknowledged to be key figures in their particular fields. These Subject Collections gradually accumulate articles as new issues of the journal are published and, when complete, each represents a comprehensive survey of the field it covers. Cold Spring Harbor Perspectives in Medicine is thus unmatched in its depth of coverage and represents an essential source where readers can find informed surveys and critical discussion of advances in molecular medicine.

Please visit www.perspectivesinmedicine.org for complete information about the journal.

Subject Coverage includes:

  • Addiction
  • Aging
  • Alzheimer Disease
  • Anemia
  • Antibiotic Resistance
  • Bacterial Pathogens
  • Bone Disease
  • Cancer
  • Cystic Fibrosis
  • Diabetes
  • Heart Disease
  • Hemoglobin
  • HIV
  • Influenza
  • Malaria
  • Multiple Sclerosis
  • Muscular Dystrophy
  • Parkinson's Disease
  • Prion Diseases
  • Skin Diseases
  • Schizophrenia
 
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CSH Perspectives in Biology

Online Features: CSH Perspectives in Biology – CSH Perspectives in Biology at Stanford University Libraries' HighWire Press

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© 2019 • ISSN: 1943-0264; Volume 11 includes full online access
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January - December 2019, 12 monthly issues
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A new online publication for the molecular life sciences

Cold Spring Harbor Perspectives in Biology provides the scientific community with comprehensive, systematic surveys of topics in the molecular life sciences where research is breaking new ground

In July 2009, Cold Spring Harbor Laboratory Press launched a new monthly journal, Cold Spring Harbor Perspectives in Biology, that provides comprehensive, systematically structured surveys of research in exciting areas of molecular and cellular biology, genetics, developmental biology, neuroscience, cancer biology, and molecular pathology.

For decades, Cold Spring Harbor Laboratory has complemented its groundbreaking research with publication of a variety of highly prestigious titles written and edited by leading scientists. These include the journals Genes & Development and Genome Research, the bible of research methods, Molecular Cloning, online teaching resources, and numerous other laboratory manuals, monographs, handbooks, journals, and textbooks.

Cold Spring Harbor Perspectives in Biology (http://www.cshperspectives.org; ISSN 1943-0264) is the latest, and perhaps most ambitious, addition to this stable. Its depth of coverage is unmatched, spanning the entire spectrum of the molecular life sciences and therefore providing an essential resource for all areas of bioscience research.

According to the journal's Executive Editor, Richard Sever, who has worked on traditional review journals including the Current Opinion and Trends titles, Cold Spring Harbor Perspectives in Biology has a new and unique approach. "There are many review articles published each year, but they're usually on one particular aspect of one particular field," he says. "CSH Perspectives is different. We cover subjects by asking experts to consider how best to structure a comprehensive survey of their field, and then commission articles from all the key figures in that field. And we cover everything in bioscience from Alzheimer's to plant biology."

CSH Perspectives articles are all commissioned as �collections� by a board of eminent academic editors and gradually accumulate online at the journal's website each month as they are accepted and published. The debut issue features articles commissioned by Elaine Fuchs, Michael Karin, W. James Nelson, and Peter Lawrence and includes contributions from Nobel laureate David Baltimore, molecular motor expert Nobutaka Hirokawa, and developmental biologist Jim Smith. These set the stage for subject collections on symmetry breaking, morphogen gradients, cell junctions, and the immune signaling molecule NF-kB. Next in the pipeline are articles on the origin of life, the p53-family of tumor suppressors, the nucleus, and immune tolerance.

The new publication is produced online in partnership with Stanford University Library's HighWire Press, taking advantage of their new H20 platform. The state-of-the-art website includes HTML and PDF views, high-resolution artwork, and video material, along with a host of novel features such as author updates, commenting options, and Twitter-powered news feeds.

 
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CSH Protocols

Edited By Richard Sever, Cold Spring Harbor Laboratory Press

Online Features: Internet edition – Cold Spring Harbor Protocols at Stanford University Libraries' HighWire Press

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© 2019 • ISSN: 1559-6095; Volume 14; includes full online access
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January - December 2019, 12 monthly issues
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  • The online source of trusted techniques in molecular and cellular biology
  • Contains new and classic protocols presented step-by-step with recipes and troubleshooting
  • Frequently updated and annotated
  • Interactive, customizable, and fully searchable

The development of CSH Protocols is a response to requests from scientists for authoritative information about techniques with a broad editorial scope, delivered through a state-of-the-art online interface. At this site, you will find methods from Molecular Cloning along with selected protocols from many of our best-selling manuals, such as Cells and Antibodies, as well as protocols from Cold Spring Harbor's renowned on-site courses. In addition, you will discover new cutting-edge protocols submitted by and commissioned from laboratories worldwide. A peer-reviewed online journal, CSH Protocols is updated monthly.

Features include:
  • Step-by-step, uniformly structured formats for ease of use and printing, with clearly linked materials, cautions, recipes, and troubleshooting
  • Customizable, topic-based e-mail alerts for the latest updates in a particular field
  • Personal folders for storing favorite protocols and searches
  • Navigation tools including a specifically designed taxonomy for browsing and a variety of full-text search options
  • A kit search tool for fast access to time-saving resources
  • An online manuscript submission system for authors to contribute new protocols

CSH Protocols — More Than Just Methods.

Visit www.cshprotocols.org for more details on features, subscriptions, and manuscript submission.

  • Available exclusively via institutional site license
  • ISSN 1559-6095 / online, monthly

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RNA

Edited By Timothy W. Nilsen, Editor-in-Chief, Case Western Reserve University; Thomas R. Cech, Howard Hughes Medical Institute; David Engelke, University of Michigan; Eric Westhof, CNRS Strasbourg; Marvin Wickens, University of Wisconsin

Online Features: Internet edition – RNA Online at Stanford University Libraries' HighWire Press

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© 2019 • ISSN 1355-8382; Volume 25; includes full online access.
FREE TRIAL ACCESS offer for libraries! Contact cironek@cshl.edu.
(Published by CSHL Press for The RNA Society)
January - December 2019, 12 monthly issues
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RNA, the publication of the RNA Society, publishes high quality research papers that provide significant new insight into any area of RNA biology, including molecular biology, cell biology, biochemistry, bioinformatics, genetics and evolution. RNA publishes two research formats, articles and short reports. In addition, the journal publishes novel methodologies, reviews and perspectives. RNA provides a unique resource to all members of the RNA community and those that wish to keep abreast of this quickly moving area.

 
 

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Calcium Signaling, Second Edition


Subject Area(s):  Cell BiologyBiochemistry

Edited by Geert Bultynck, KU Leuven; Martin D. Bootman, The Open University; Michael J. Berridge, The Babraham Institute; Grace E. Stutzmann, Rosalind Franklin University / The Chicago Medical School

Due August 2019 • 325 pages (approx.), illustrated, index
Hardcover • $135 108.00
ISBN  978-1-621822-92-9
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  •     Contents    

Description

Calcium signals—rapid changes in calcium ion concentration—are carefully orchestrated by a suite of proteins that transport and bind to calcium ions inside cells. These signals influence virtually all aspects of animal development and physiology, from fertilization and cell differentiation to muscle contraction and nerve impulses. Aberrant calcium signaling is associated with various pathologies (e.g., cancer and neurodegeneration) as well as aging.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive update on all facets of calcium signaling. The contributors discuss the components and activities of the various calcium-sequestering organelles inside cells, the dynamic interactions that lead to spatiotemporally distinct signals in different circumstances, and the downstream effector mechanisms that translate the signals into biological outcomes. Recent advances in the field (e.g., structural insights into the functions of certain calcium channels) are emphasized throughout.

The authors also discuss normal and perturbed calcium signaling during fertilization, development, physiology, regeneration, aging, and disease. This volume is therefore an indispensable reference for biochemists, cell and developmental biologists, and physiologists seeking a comprehensive treatment of calcium signaling.

Contents

Preface
CALCIUM ENTRY
Transient Receptor Potential (TRP) Channels and Calcium Signaling
Laura Vangeel and Thomas Voets
SOC
Richard Lewis
ER-PM Junction: A hub for Agonist-Regulation of Ca2+ Entry
Hwei Ling Ong and Indu Suresh Ambudkar
CALCIUM RELEASE
Structure and Function of IP3 Receptors
David L. Prole and Colin W. Taylor
NAADP Receptors
Antony Galione
Calcium Leak Channels
Martin Bootman and Geert Bultynck
Signaling through Ca2+ Microdomains from Store-Operated CRAC Channels
Pradeep Barak and Anant B. Parekh
CALCIUM STORES AND CALCIUM TRANSPORT MACHINES
Primary Active Ca2+ Transport Systems in Health and Disease
Jialin Chen, Aljona Sitsel, Veronick Benoy, M. Rosario Sepúlveda, and Peter Vangheluwe
The Roles of Mitochondria in Calcium Signaling: Molecules Involved in Mitochondrial Calcium Uptake
Rosario Rizzuto
Cytoplasmic and Mitochondrial Calcium Signaling: A Two-Way Relationship
Benjamin Wacquier, Laurent Combettes, and Geneviève Dupont
Lysosomal Calcium Signaling
Emry Lloyd-Evans
Cytosolic Ca2+ Buffers are Inherently Ca2+ Signal Modulators
Beat Schwaller
Organellar Calcium Handling in the Cellular Reticular Network
Wen-An Wang, Luis B. Agellon, and Marek Michalak
DOWNSTREAM EFFECTORS OF CALCIUM
Interplay Between Calcium and cAMP Signaling
Aldebaran Hofer
Structural Insights Into the Regulation of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII)
Moitrayee Bhattacharyya, Deepti Karandur, and John Kuriyan
Calcium Sensors in Neuronal Function and Dysfunction
Robert D. Burgoyne, Nordine Helassa, Hannah V. McCue, and Lee P. Haynes
Identifying New Substrates and Functions for an Old Enzyme: Calcineurin
Jagoree Roy and Martha S. Cyert
PHYSIOLOGICAL PROCESSES REGULATED BY CALCIUM
Calcium and Fertilization
Rafael Fissore
Role of Two-Pore Channels in Embryonic Development and Cellular Differentiation
Sarah E. Webb, Jeffrey J. Kelu, and Andrew L. Miller
Functional Consequences of Calcium-Dependent Synapse-to-Nucleus Communication: Focus on Transcription-Dependent Metabolic Plasticity
Anna M. Hagenston, Hilmar Bading, and Carlos Bas-Orth
Calcium Signaling in Cardiomyocyte Function
Guillaume Gilbert, Kateryna Demydenko, Eef Dries, Rosa Doñate Puertas, Karin Sipido, and H. Llewelyn Roderick
Astroglial Calcium Signaling in Ageing and Alzheimer’s Disease
Alexei Verkhratsky
Ca2+ Signaling and Regeneration
Jonathan S. Marchant
CALCIUM AND DISEASE
Creating a New Cancer Therapeutic Agent by Targeting the Interaction Between Bcl-2 and IP3 Receptors
Clark W. Distelhorst and Martin D. Bootman
The Calcium Signaling Toolkit in Cancer: Remodeling and Targeting
Sarah J. Roberts-Thomson, Silke B. Chalmers, and Gregory R. Monteith
Calcium and Neuropathology
Grace E. Stutzman
Calcium Signaling and Tissue Calcification
Diane Proudfoot
Ca2+ Signaling in Exocrine Cells
Malini Ahuja, Woo Young Chung, Wei-Yin Lin, Beth A. McNally, and Shmuel Muallem
Index
   

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Brains & Behavior: Order and Disorder in the Nervous System

(Cold Spring Harbor Symposia on Quantitative Biology LXXXIII)

Book Series:  Cold Spring Harbor Symposia on Quantitative Biology
Subject Area(s):  Human Biology and DiseaseNeurobiology

Edited by David Stewart, Cold Spring Harbor Laboratory; Bruce Stillman, Cold Spring Harbor Laboratory

Due September 2019 • Illustrated, index
Paperback • $129 103.20
ISBN  978-1-621823-36-0
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The 2018 Symposium on Brains & Behavior: Order & Disorder in the Nervous System explores the tremendous recent progress in neuroscience and technologies and how these advances may be used to improve brain health and address psychiatric and neurological disorders.
   

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Brains & Behavior: Order and Disorder in the Nervous System

(Cold Spring Harbor Symposia on Quantitative Biology LXXXIII)

Book Series:  Cold Spring Harbor Symposia on Quantitative Biology
Subject Area(s):  Human Biology and DiseaseNeurobiology

Edited by David Stewart, Cold Spring Harbor Laboratory; Bruce Stillman, Cold Spring Harbor Laboratory

Due September 2019 • Illustrated, index
Hardcover • $318 254.40
ISBN  978-1-621823-35-3
You save: 20%
You will receive free shipping on this item at checkout.
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The 2018 Symposium on Brains & Behavior: Order & Disorder in the Nervous System explores the tremendous recent progress in neuroscience and technologies and how these advances may be used to improve brain health and address psychiatric and neurological disorders.
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