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Stem Cells: From Biological Principles to Regenerative Medicine


Book Series:  A Cold Spring Harbor Perspectives in Biology Collection
Subject Area(s):  Developmental BiologyCell Biology

Edited by Cristina Lo Celso; Kristy Red-Horse; Fiona M. Watt

Due November 2019 • 250 pages (approx.), illustrated, index
Hardcover • $135 108.00
ISBN  978-1-621823-39-1
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  •     Description    
  •     Contents    

Description

Stem cells are multipotent cells that sustain and repair tissues by dividing and differentiating to form the various different cell types normally present. Embryonic stem cells are capable of differentiating into any cell type, whereas adult stem cells are typically restricted to a particular lineage. This book examines recent progress in our understanding of the biology of these cells, how they are regulated, and opportunities for using them in disease therapies.

Contents

Preliminary
Modeling brain disorders using IPS cells
Rusty Gage
Organoids
Madeline Lancaster
Combined gene and cell therapy for disease of the epidermis
Michele De Luca
Cell and gene therapies for blindness
Robin Ali
New generations of biomaterials
Cole DeForest
Stem cell plasticity
Jayaraj Rajagopal
Stem cells therapy for diabetes
Doug Melton
Reprograming liver into pancreas
Francesca Spagnoli
Stem Cell DNA Damage in the Context of Aging and Cancer Initiation
Allison Bardin
Lung stem cell niche
Tushar Desai
Unexpected progenitor cells by lineage tracing/live imaging
Karina Yaniv
Pre-implantation embryos: Mechanical regulation/cell biology/cell fate decision making
Nicolas Platcha
Advancing Stem Cell Research Through Multimodal Single Cell Analysis
Iwo Kucinski and Berthold Gottgens
Live imaging of stem cells
Jacco van Rheenen
Sperm stem cells
Shosei Yoshida
Systems biology of stem cells
Benjamin Simons
Hematopoiesis
Kateri Moore and Saghi Ghaffari
Index