Cell Survival and Cell Death, Second Edition

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Click to Enlarge				Cell Survival and Cell Death, Second Edition Book Series: A Cold Spring Harbor Perspectives in Biology Collection Subject Area(s): Cell Biology; Cancer Biology Edited by Kim Newton, Genentech; James M. Murphy, Walter and Eliza Hall Institute of Medical Research; Edward A. Miao, University of North Carolina at Chapel Hill

				Due February 2020 • 300 pages (approx.), illustrated, index Paperback • ~~$135~~ 108.00 ISBN 978-1-621823-55-1 You save: 20% You will receive free shipping on this item at checkout. Free shipping offer applies to direct website purchases by individual U.S. and Canada customers only.

Description Contents Description Cell death plays a critical role in development, normal physiology, and many diseases, including cancer. This new edition on the subject provides a state-of-the-art summary of our understanding of the signaling mechanisms that regulate cell survival and cell death, along with the molecular mechanisms underlying the various different death processes seen in cells. Contents Preliminary BAX, BAK, and BOK; A Coming of Age for the BCL-2 Family Effector Proteins Tudor Moldoveanu and Peter E. Czabotar BH3 Mimetics: Targeting Pro-Survival Bcl2 Family Members for the Treatment of Cancer David Huang and Wayne Fairbrother Mechanisms of Caspase Activation Marion Macfarlane Cracking the Cell Death Code Carla V. Rothlin and Sourav Ghosh Phagocyte responses to cell death in flies Andrew J. Davidson and Will Wood Multi-tasking Kinase RIPK1 Regulates Cell Death and Inflammation Kim Newton The Killer Pseudokinase MLKL James M. Murphy Targeting Death Receptors in Cancer and Inflammation Henning Walczak Recent Insights on Inflammasomes, Gasderin Pores, and Pyroptosis Xia, Louis Robert Hollingsworth IV, and Hao Wu A20 at the Crossroads of Cell Death, Inflammation, and Autoimmunity Arne Martens and Geert van Loo Regulation of Cell Death and Immunity by XIAP Philipp J. Jost and Domagoj Vucic Cell Death and Neurodegeneration Benjamin J. Andreone, Martin Larhammar, and Joseph W. Lewcock Evolution of the Cell Death Machinery Kay Hofmann Programmed Cell Death in the Evolutionary Race Against Bacterial Virulence Factors Carolyn A. Lacey and Edward A. Miao How Viral Pathogens Subvert the Cell Death Machinery Bill Kaiser Cell Cycle Crosstalk with Caspases and Their Substrates Patrick Connolly, Irmina García-Carpio, and Andreas Villunger The Hypersensitive Response Cell Death in Plant Immunity Eugenia Pitsii, Ujjal J. Phukan, and Núria S. Coll Dysregulation of Cell Death in Chronic Human Inflammation Yue Li, Christoph Klein, and Daniel Kotlarz Neutrophil Extracellular Traps in Host Defense Sabrina Sofia Burgener and Kate Schroder Index