Neurogenesis

Click to Enlarge				Neurogenesis Book Series: A Cold Spring Harbor Perspectives in Biology Collection Subject Area(s): Neurobiology Edited by Fred H. Gage, The Salk Institute for Biological Studies, San Diego, California; Gerd Kempermann, Center for Regenerative Therapies, Dresden, Germany; Hongjun Song, Johns Hopkins School of Medicine, Baltimore, Maryland

				© 2015 • 542 pages, illustrated (71 color, 9 B&W), index Hardcover • ~~$135~~ 94.50 ISBN 978-1-621820-74-1 You save: 30% You will receive free shipping on this item at checkout. Free shipping offer applies to direct website purchases by individual U.S. and Canada customers only.

Description Contents Description In discrete locations of the adult brain, new neurons are born from stem cells that differentiate, migrate, and integrate into the existing neural network. This process is implicated in normal brain functions such as memory formation and is disrupted in many disease states, including Alzheimer's, schizophrenia, and depression. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a state-of-the-art account of the sophisticated neurogenic processes in the adult mammalian brain—particularly in the hippocampus and olfactory bulb. Contributors review the properties of neural precursor subtypes, the molecular mechanisms that underlie their maturation, the influence of external stimuli (e.g., exercise), the functions of the newborn neurons in the brain, and the factors that determine their survival or elimination. The differences between embryonic and adult neurogenesis, noncanonical sites of neurogenesis, and evolutionary aspects of neurogenesis are discussed, as are methods and models for studying neurogenic processes. The authors also explore how neurogenesis is disrupted in various neurological and psychiatric diseases, as well as the potential to harness neurogenic processes for therapeutic interventions (e.g., repairing a stroke-damaged brain). This volume will therefore be useful for neurobiologists, cell and developmental biologists, and those with clinical interests. Contents Preface METHODS Neurogenesis: A Prologue Gerd Kempermann, Hongjun Song, and Fred H. Gage Detection and Phenotypic Characterization of Adult Neurogenesis H. Georg Kuhn, Amelia J. Eisch, Kirsty Spalding, and Daniel A. Peterson In Vitro Models for Neurogenesis Hassan Azari and Brent A. Reynolds Viral and Transgenic Reporters and Genetic Analysis of Adult Neurogenesis Grigori Enikolopov, Linda Overstreet-Wadiche, and Shaoyu Ge CELLULAR MECHANISMS Neurogenesis in the Adult Hippocampus Gerd Kempermann, Hongjun Song, and Fred H. Gage The Adult Ventricular–Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis Daniel A. Lim and Arturo Alvarez-Buylla Diversity of Neural Precursors in the Adult Mammalian Brain Michael A. Bonaguidi, Ryan P. Stadel, Daniel A. Berg, Jiaqi Sun, Guo-li Ming, and Hongjun Song Noncanonical Sites of Adult Neurogenesis in the Mammalian Brain David M. Feliciano, Angélique Bordey, and Luca Bonfanti MOLECULAR MECHANISMS Neurogenesis in the Developing and Adult Brain—Similarities and Key Differences Magdalena Götz, Masato Nakafuku, and David Petrik Transcription-Factor-Dependent Control of Adult Hippocampal Neurogenesis Ruth Beckervordersandforth, Chun-Li Zhang, and Dieter Chichung Lie Control of Adult Neurogenesis by Short-Range Morphogenic-Signaling Molecules Youngshik Choe, Samuel J. Pleasure, and Helena Mira Control of Cell Survival in Adult Mammalian Neurogenesis H. Georg Kuhn Maturation and Functional Integration of New Granule Cells into the Adult Hippocampus Nicolas Toni and Alejandro F. Schinder Genetics and Epigenetics in Adult Neurogenesis Jenny Hsieh and Xinyu Zhao Engineering of Adult Neurogenesis and Gliogenesis Benedikt Berninger and Sebastian Jessberger Regulation of Adult Neurogenesis and Plasticity by (Early) Stress, Glucocorticoids, and Inflammation Paul J. Lucassen, Charlotte A. Oomen, Eva F.G. Naninck, Carlos P. Fitzsimons, Anne-Marie van Dam, Boldizsár Czeh, and Aniko Korosi Activity Dependency and Aging in the Regulation of Adult Neurogenesis Gerd Kempermann Neuronal Circuitry Mechanisms Regulating Adult Mammalian Neurogenesis Juan Song, Reid H.J. Olsen, Jiaqi Sun, Guo-li Ming, and Hongjun Song FUNCTIONAL SIGNIFICANCE Adult Olfactory Bulb Neurogenesis Pierre-Marie Lledo and Matt Valley Interaction between Neurogenesis and Hippocampal Memory System: New Vistas Djoher Nora Abrous and Jan Martin Wojtowicz Computational Modeling of Adult Neurogenesis James B. Aimone NEUROLOGICAL AND PSYCHIATRIC DISEASES Functional Differentiation of Adult-Born Neurons along the Septotemporal Axis of the Dentate Gyrus Melody V Wu, Amar Sahay, Ronald S. Duman, and René Hen Adult Neurogenesis in Neurodegenerative Diseases Beate Winner and Jürgen Winkler Adult Neurogenesis and Psychiatric Disorders Eunchai Kang, Zhexing Wen, Hongjun Song, Kimberly M. Christian, and Guo-li Ming Epilepsy and Adult Neurogenesis Sebastian Jessberger and Jack M. Parent Neurogenesis following Stroke Affecting the Adult Brain Olle Lindvall and Zaal Kokaia COMPARATIVE NEUROGENESIS AND EVOLUTIONARY ASPECTS Adult Neurogenesis in Fish Julia Ganz and Michael Brand Neurogenesis in the Adult Avian Song-Control System Eliot A. Brenowitz and Tracy A. Larson Adult Neurogenesis in Humans Olaf Bergmann, Kristy L. Spalding, and Jonas Frisen Adult Hippocampal Neurogenesis in Natural Populations of Mammals Irmgard Amrein Adult Neurogenesis: An Evolutionary Perspective Gerd Kempermann Index

Neurogenesis

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