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Lung Cancer: Disease Biology and Its Potential for Clinical Translation

Book Series:  A Cold Spring Harbor Perspectives in Medicine Collection
Subject Area(s):  Cell BiologyCancer Biology

Edited by Christine M. Lovly; David P. Carbone; John D. Minna

Due December 2021 • 250 pages (approx.), illustrated, index
Hardcover • $135 94.50
ISBN  978-1-621823-73-5
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  •     Description    
  •     Contents    


Lung cancer affects millions of people worldwide and is the most common cause of cancer-related death in men. This volume investigates the biological basis of lung cancer, the risk factors involved, and recent advances in treatment strategies.


David Carbone, Christine Lovly, and John Minna
Early Diagnosis and Screening for Lung Cancer
Humam Kadara, Lihn M. Tran, Anil Vachani, Bin Liu, Xianghong J. Zhou, Ansam Sinjab, Shuo Li, Steven M. Dubinett, and Kostyantyn Krysan
Molecular Pathology of Lung Cancer
James Saller and Theresa A. Boyle
Preclinical Models for the Study of Lung Cancer Pathogenesis and Therapy Development
Anna Arnal Estape, Giorgia Foggetti, Jacqueline Starrett, Don Nguyen, and Katerina Politi
Targeting Epigenetics in Lung Cancer
Yvonne L. Chao and Chad V. Pecot
Lung Cancer Metabolism
Gina M. DeNicola and David B. Shackelford
Tumor Immunology and Immunotherapy of Non-Small Cell Lung Cancer
Tina Cascone, Jared Fradette, Monika Pradhan, and Don L. Gibbons
Stem Cell Biology and Lineage Plasticity
David Carbone and Carla Kim
Advances in SCLC Translational Research
Benjamin J. Drapkin and Charles M. Rudin
Application of Radiomics and AI for Lung Cancer Precision Medicine
Ilke Tunali, Robert J. Gillies, and Matthew B. Schabath
Radiation Therapy in Non-Small Cell Lung Cancer
Michael Dohopolski, Sujana Gottumukkala, Daniel Gomez, and Puneeth Iyengar
Lung Cancer Computational Biology and Resources
Yang Xie
Concluding Remarks
David Carbone, Christine Lovly, and John Minna