Click to Enlarge
Download Free Excerpts from Calcium Signaling: Download Preface and Contents Download Index
Download Free Excerpts from Calcium Signaling:
Download Preface and Contents Download Index
© 2011 499 pp., illus. (71 4C color images and 11 B&W images), index Hardcover $135 54.00 ISBN 978-0-87969-903-1 You save: 60% Discounts apply to direct website purchases by individual US customers only; all sales are final.
Calcium ions play a critical role in signaling in a wide variety of cells and tissues, including muscle, immune cells, neurons, the liver, and oocytes. They can enter the cytoplasm from the extracellular environment or from intracellular stores and control the activity of numerous enzymes, other signaling molecules, transcription factors, and cytoskeletal components.
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology explores the channels and pumps that transport calcium between different compartments and the regulation of calcium fluxes. The contributors discuss calcium buffers and sensors and how these produce distinct spatiotemporal calcium signals in different circumstances.
Including discussions of calcium signaling during development and normal physiology, as well as perturbed signaling in diseases such as diabetes, neurodegeneration, and atherosclerosis, the volume is an indispensable reference for biochemists, cell and developmental biologists, and physiologists seeking a comprehensive treatment of calcium biology.