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Landmark Glycobiology textbook now available in print and online


Glycobiology -- the study of the structure, biosynthesis, biology, and evolution of glycans (the sugar chains synthesized by all living cells) -- is a fast growing field in the natural sciences, with broad relevance to many areas of basic research, biomedicine, and biotechnology.

The third edition features an expanded international editorial board and panel of contributing authors, representing a wide range of expertise in emerging areas. Other key enhancements include a broadened focus on all lineages of life-forms in nature, increased coverage of topics, ranging from biology and medicine to chemistry and materials science, and in-depth attention to informatics and the exploration of the glycome.

Advance praise from leaders in the field affirms that this title is a critical resource for all researchers:
"The third edition of Essentials of Glycobiology may be life changing for scientists who have not yet engaged with glycobiology, and will certainly be a treasured resource for those who already have," said Bruce Beutler, Nobel Laureate in Medicine, 2011.

"Written by authoritative leaders in the field, we learn how this knowledge has been rapidly advancing, and see possibilities for real breakthroughs in understanding and therapy," said Peter C. Doherty, Nobel Laureate in Medicine, 1996.

Like the first and second editions of Essentials of Glycobiology, the third edition is freely available on the National Center for Biotechnology Information's (NCBI's) online bookshelf, hosted by the U.S. National Library of Medicine. The free online book is again released simultaneously with a print edition published by Cold Spring Harbor Laboratory Press (CSHLP). Print copies can be ordered at the CSHLP website, Amazon, and other book retailers.

The book's innovative content and publishing models are the result of an ongoing collaboration between CSHLP, the book's Consortium of Glycobiology Editors led by Dr. Ajit Varki, University of California at San Diego, CSHLP, and NCBI. The Glycobiology Research and Training Center at UC San Diego and the Programs of Excellence in Glycoscience of the National Heart, Lung, and Blood Institute (NHLBI) also contributed resources toward the project. The editors of the new edition will be assigning all proceeds from sales of the print book to further the impact of this resource in the glycoscience community.

Please visit CSHLP for more information and details on how to order the print book:

Please visit the NCBI Bookshelf for access to the free online edition:

About Cold Spring Harbor Laboratory Press
Cold Spring Harbor Laboratory Press is an internationally renowned not-for-profit publisher of books, journals, and electronic media, located on Long Island, New York. Since 1933, it has furthered the advance and spread of scientific knowledge in all areas of genetics and molecular biology, including cancer biology, plant science, bioinformatics, and neurobiology. It is a division of Cold Spring Harbor Laboratory, an innovator in life science research and the education of scientists, students, and the public. All revenue from sales of CSHL Press publications supports research at Cold Spring Harbor Laboratory.

IMAGE: This is a stereo view of a crystal structure (1TB6) of the complex between antithrombin (purple), thrombin (blue), and a 16-mer heparin mimetic (SR123781A). The proteins are shown in cartoon with a semitransparent surface, and the oligosaccharide is represented as ball-and-stick, with carbon in green, oxygen in red, and sulfur in yellow. The oligosaccharide is composed of an antithrombin-specific pentasaccharide based on idraparanux, an uncharged seven-saccharide unit linker, and a highly sulfated four residue thrombin-binding unit.

Courtesy of Jim Huntington, Professor of Molecular Haemostasis, University of Cambridge.

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